Ionophoretically applied substance P activates hamster suprachiasmatic nucleus neurons

Hugh D. Piggins; David J. Cutler; Benjamin Rusak

doi:10.1016/0361-9230(95)00027-C

Ionophoretically applied substance P activates hamster suprachiasmatic nucleus neurons

Hugh D. Piggins, David J. Cutler, Benjamin Rusak

Medicine

Medicine

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

21 Citas (Scopus)

Resumen

Ionophoretic ejection of substance P (SP) activated 31% and suppressed 9% of hamster suprachiasmatic nucleus (SCN) cells in vitro. Hamster SCN cells did not demonstrate variation in sensitivity to SP across the circadian phases tested. SP modulated the response of 47% of hamster SCN cells to the excitatory amino acid (EAA) agonists glutamate and N-methyl-d-aspartate (NMDA). The results indicate that SP can alter both the spontaneous and EAA-evoked firing rate characteristics of hamster SCN neurons.

Idioma original	English
Páginas (desde-hasta)	475-479
Número de páginas	5
Publicación	Brain Research Bulletin
Volumen	37
N.º	5
DOI	https://doi.org/10.1016/0361-9230(95)00027-C
Estado	Published - 1995

ASJC Scopus Subject Areas

General Neuroscience

Acceder al documento

10.1016/0361-9230(95)00027-C

Otros archivos y enlaces

Citar esto

@article{7f2826ebfe854684a9d5a796ef7ed196,

title = "Ionophoretically applied substance P activates hamster suprachiasmatic nucleus neurons",

abstract = "Ionophoretic ejection of substance P (SP) activated 31% and suppressed 9% of hamster suprachiasmatic nucleus (SCN) cells in vitro. Hamster SCN cells did not demonstrate variation in sensitivity to SP across the circadian phases tested. SP modulated the response of 47% of hamster SCN cells to the excitatory amino acid (EAA) agonists glutamate and N-methyl-d-aspartate (NMDA). The results indicate that SP can alter both the spontaneous and EAA-evoked firing rate characteristics of hamster SCN neurons.",

author = "Piggins, {Hugh D.} and Cutler, {David J.} and Benjamin Rusak",

year = "1995",

doi = "10.1016/0361-9230(95)00027-C",

language = "English",

volume = "37",

pages = "475--479",

journal = "Brain Research Bulletin",

issn = "0361-9230",

publisher = "Elsevier Inc.",

number = "5",

}

TY - JOUR

T1 - Ionophoretically applied substance P activates hamster suprachiasmatic nucleus neurons

AU - Piggins, Hugh D.

AU - Cutler, David J.

AU - Rusak, Benjamin

PY - 1995

Y1 - 1995

N2 - Ionophoretic ejection of substance P (SP) activated 31% and suppressed 9% of hamster suprachiasmatic nucleus (SCN) cells in vitro. Hamster SCN cells did not demonstrate variation in sensitivity to SP across the circadian phases tested. SP modulated the response of 47% of hamster SCN cells to the excitatory amino acid (EAA) agonists glutamate and N-methyl-d-aspartate (NMDA). The results indicate that SP can alter both the spontaneous and EAA-evoked firing rate characteristics of hamster SCN neurons.

AB - Ionophoretic ejection of substance P (SP) activated 31% and suppressed 9% of hamster suprachiasmatic nucleus (SCN) cells in vitro. Hamster SCN cells did not demonstrate variation in sensitivity to SP across the circadian phases tested. SP modulated the response of 47% of hamster SCN cells to the excitatory amino acid (EAA) agonists glutamate and N-methyl-d-aspartate (NMDA). The results indicate that SP can alter both the spontaneous and EAA-evoked firing rate characteristics of hamster SCN neurons.

UR - http://www.scopus.com/inward/record.url?scp=0029064457&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029064457&partnerID=8YFLogxK

U2 - 10.1016/0361-9230(95)00027-C

DO - 10.1016/0361-9230(95)00027-C

M3 - Article

C2 - 7543357

AN - SCOPUS:0029064457

SN - 0361-9230

VL - 37

SP - 475

EP - 479

JO - Brain Research Bulletin

JF - Brain Research Bulletin

IS - 5

ER -

Ionophoretically applied substance P activates hamster suprachiasmatic nucleus neurons

Resumen

ASJC Scopus Subject Areas

Acceder al documento

Otros archivos y enlaces

Huella

Citar esto