Research output per year
Research output per year
- 1 - 50 out of 278 results
Search results
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2018
Lycium barbarum Polysaccharide Supplementation Improves Alcoholic Liver Injury in Female Mice by Inhibiting Stearoyl-CoA Desaturase 1
Wang, F., Tipoe, G. L., Yang, C., Nanji, A. A., Hao, X., So, K. F. & Xiao, J., Jul 2018, In: Molecular Nutrition and Food Research. 62, 13, 1800144.Research output: Contribution to journal › Article › peer-review
30 Citations (Scopus) -
2015
Cyclooxygenase-1 serves a vital hepato-protective function in chemically induced acute liver injury
Xiao, J., Liong, E. C., Huang, H., Tse, W. O., Lau, K. S., Pan, J., Nanji, A. A., Fung, M. L., Xing, F. & Tipoe, G. L., Feb 1 2015, In: Toxicological Sciences. 143, 2, p. 430-440 11 p.Research output: Contribution to journal › Article › peer-review
Open Access28 Citations (Scopus) -
The adiponectin-SIRT1-AMPK pathway in alcoholic fatty liver disease in the rat
Jiang, Z., Zhou, J., Zhou, D., Zhu, Z., Sun, L. & Nanji, A. A., Mar 1 2015, In: Alcoholism: Clinical and Experimental Research. 39, 3, p. 424-433 10 p.Research output: Contribution to journal › Article › peer-review
46 Citations (Scopus) -
2014
Epigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in non-alcoholic fatty liver disease rat model through TGF/SMAD, PI3 K/Akt/FoxO1, and NF-kappa B pathways
Xiao, J., Ho, C. T., Liong, E. C., Nanji, A. A., Leung, T. M., Lau, T. Y. H., Fung, M. L. & Tipoe, G. L., Feb 2014, In: European Journal of Nutrition. 53, 1, p. 187-199 13 p.Research output: Contribution to journal › Article › peer-review
182 Citations (Scopus) -
Involvement of insulin resistance in the protective effect of metformin against alcoholic liver injury
Zhu, Z., Jiang, Z., Zhou, J., Zhou, D., Wang, W., Zhao, C., Zhen, Z. & Nanji, A. A., Jun 2014, In: Alcoholism: Clinical and Experimental Research. 38, 6, p. 1510-1519 10 p.Research output: Contribution to journal › Article › peer-review
15 Citations (Scopus) -
2013
Garlic-derived S-allylmercaptocysteine is a hepato-protective agent in non-alcoholic fatty liver disease in vivo animal model
Xiao, J., Ching, Y. P., Liong, E. C., Nanji, A. A., Fung, M. L. & Tipoe, G. L., Feb 2013, In: European Journal of Nutrition. 52, 1, p. 179-191 13 p.Research output: Contribution to journal › Article › peer-review
Open Access91 Citations (Scopus) -
Hepatic response to chronic hypoxia in experimental rat model through HIF-1 alpha, activator protein-1 and NF-kappa B
Lau, T. Y. H., Xiao, J., Liong, E. C., Liao, L., Leung, T. M., Nanji, A. A., Fung, M. L. & Tipoe, G. L., Mar 15 2013, In: Histology and Histopathology. 28, 4, p. 463-471 9 p.Research output: Contribution to journal › Article › peer-review
12 Citations (Scopus) -
Long-Term Binge and Escalating Ethanol Exposure Causes Necroinflammation and Fibrosis in Rat Liver
Zhou, J. Y., Jiang, Z. A., Zhao, C. Y., Zhen, Z., Wang, W. & Nanji, A. A., Feb 2013, In: Alcoholism: Clinical and Experimental Research. 37, 2, p. 213-222 10 p.Research output: Contribution to journal › Article › peer-review
29 Citations (Scopus) -
Thromboxane Inhibitors Attenuate Inflammatory and Fibrotic Changes in Rat Liver Despite Continued Ethanol Administrations
Nanji, A. A., Liong, E. C., Xiao, J. & Tipoe, G. L., Jan 2013, In: Alcoholism: Clinical and Experimental Research. 37, 1, p. 31-39 9 p.Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus) -
2012
Cyclooxygenase inhibitors protect d-galactosamine/lipopolysaccharide induced acute hepatic injury in experimental mice model
Liong, E. C., Xiao, J., Lau, T. Y. H., Nanji, A. A. & Tipoe, G. L., Mar 2012, In: Food and Chemical Toxicology. 50, 3-4, p. 861-866 6 p.Research output: Contribution to journal › Article › peer-review
17 Citations (Scopus) -
2011
Role of nitric oxide in the regulation of fibrogenic factors in experimental liver fibrosis in mice
Leung, T. M., Fung, M. L., Liong, E. C., Lau, T. Y. H., Nanji, A. A. & Tipoe, G. L., Feb 2011, In: Histology and Histopathology. 26, 2, p. 201-211 11 p.Research output: Contribution to journal › Article › peer-review
28 Citations (Scopus) -
2010
Chronic Ethanol Consumption Results in Atypical Liver Injury in Copper/Zinc Superoxide Dismutase Deficient Mice
Curry-Mccoy, T. V., Osna, N. A., Nanji, A. A. & Donohue, T. M., Feb 2010, In: Alcoholism: Clinical and Experimental Research. 34, 2, p. 251-261 11 p.Research output: Contribution to journal › Article › peer-review
25 Citations (Scopus) -
Epigallocatechin-3-gallate (EGCG) reduces liver inflammation, oxidative stress and fibrosis in carbon tetrachloride (CCl4)-induced liver injury in mice
Tipoe, G. L., Leung, T. M., Liong, E. C., Lau, T. Y. H., Fung, M. L. & Nanji, A. A., Jun 2010, In: Toxicology. 273, 1-3, p. 45-52 8 p.Research output: Contribution to journal › Article › peer-review
248 Citations (Scopus) -
2009
Carbon tetrachloride-induced liver damage in asialoglycoprotein receptor-deficient mice
Dalton, S. R., Lee, S. M. L., King, R. N., Nanji, A. A., Kharbanda, K. K., Casey, C. A. & McVicker, B. L., Apr 1 2009, In: Biochemical Pharmacology. 77, 7, p. 1283-1290 8 p.Research output: Contribution to journal › Article › peer-review
31 Citations (Scopus) -
Dietary fatty acids and the pathogenesis of liver disease in alcoholism
Nanji, A. A., Jan 1 2009, Nutrition, Diet Therapy, and the Liver. CRC Press, p. 147-158 12 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Voluntary oral feeding of rats not requiring a very high fat diet is a clinically relevant animal model of non-alcoholic fatty liver disease (NAFLD)
Tipoe, G. L., Ho, C. T., Liong, E. C., Leung, T. M., Lau, T. Y. H., Fung, M. L. & Nanji, A. A., Sept 2009, In: Histology and Histopathology. 24, 9, p. 1161-1169 9 p.Research output: Contribution to journal › Article › peer-review
46 Citations (Scopus) -
2008
A voluntary oral ethanol-feeding rat model associated with necroinflammatory liver injury
Tipoe, G. L., Liong, E. C., Casey, C. A., Donohue, T. M., Eagon, P. K., So, H., Leung, T. M., Fogt, F. & Nanji, A. A., Apr 2008, In: Alcoholism: Clinical and Experimental Research. 32, 4, p. 669-682 14 p.Research output: Contribution to journal › Article › peer-review
41 Citations (Scopus) -
A voluntary oral-feeding rat model for pathological alcoholic liver injury
Tipoe, G. L., Liong, E. C., Leung, T. M. & Nanji, A. A., 2008, Alcohol: Methods and Protocols. Humana Press, p. 11-31 21 p. (Methods in Molecular Biology; vol. 447).Research output: Chapter in Book/Report/Conference proceeding › Chapter
13 Citations (Scopus) -
Endothelial nitric oxide synthase is a critical factor in experimental liver fibrosis
Leung, T. M., Tipoe, G. L., Liong, E. C., Lau, T. Y. H., Fung, M. L. & Nanji, A. A., Aug 2008, In: International Journal of Experimental Pathology. 89, 4, p. 241-250 10 p.Research output: Contribution to journal › Article › peer-review
41 Citations (Scopus) -
Increased severity of alcoholic liver injury in female verses male rats: A microarray analysis
Sharma, M. R., Polavarapu, R., Roseman, D., Patel, V., Eaton, E., Kishor, P. B. K. & Nanji, A. A., Feb 2008, In: Experimental and Molecular Pathology. 84, 1, p. 46-58 13 p.Research output: Contribution to journal › Article › peer-review
17 Citations (Scopus) -
Role of the fractalkine receptor CX3CR1 polymorphisms V249I and T280M as risk factors for early-onset coronary artery disease in patients with no classic risk factors
Nassar, B. A., Nanji, A. A., Ransom, T. P., Rockwood, K., Kirkland, S. A., MacPherson, K., Connelly, P. W., Johnstone, D. E., O'Neill, B. J., Bata, I. R., Andreou, P. & Title, L. M., 2008, In: Scandinavian Journal of Clinical and Laboratory Investigation. 68, 4, p. 286-291 6 p.Research output: Contribution to journal › Article › peer-review
12 Citations (Scopus) -
2007
Fatty acids and liver disease
Nanji, A. A. & Nassar, B. A., Jan 1 2007, Fatty Acids in Foods and their Health Implications, Third Edition. CRC Press, p. 1007-1018 12 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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L-Buthionine (S,R) sulfoximine depletes hepatic glutathione but protects against ethanol-induced liver injury
Donohue, T. M., Curry-McCoy, T. V., Todero, S. L., White, R. L., Kharbanda, K. K., Nanji, A. A. & Osna, N. A., Jun 2007, In: Alcoholism: Clinical and Experimental Research. 31, 6, p. 1053-1060 8 p.Research output: Contribution to journal › Article › peer-review
27 Citations (Scopus) -
Lysosomal leakage and lack of adaptation of hepatoprotective enzyme contribute to enhanced susceptibility to ethanol-induced liver injury in female rats
Donohue, T. M., Curry-McCoy, T. V., Nanji, A. A., Kharbanda, K. K., Osna, N. A., Radio, S. J., Todero, S. L., White, R. L. & Casey, C. A., Nov 2007, In: Alcoholism: Clinical and Experimental Research. 31, 11, p. 1944-1952 9 p.Research output: Contribution to journal › Article › peer-review
32 Citations (Scopus) -
2006
Expression and functions of vasoactive substances regulated by hypoxia-inducible factor-1 in chronic hypoxemia
Tipoe, G. L., Lau, T. Y. H., Nanji, A. A. & Fung, M. L., Jul 2006, In: Cardiovascular and Hematological Agents in Medicinal Chemistry. 4, 3, p. 199-218 20 p.Research output: Contribution to journal › Review article › peer-review
26 Citations (Scopus) -
Inhibitors of inducible nitric oxide (NO) synthase are more effective than an NO donor in reducing carbon-tetrachloride induced acute liver injury
Tipoe, G. L., Leung, T. M., Liong, E., So, H., Leung, K. M., Lau, T. Y. H., Tom, W. M., Fung, M. L., Fan, S. T. & Nanji, A. A., Oct 2006, In: Histology and Histopathology. 21, 11-12, p. 1157-1165 9 p.Research output: Contribution to journal › Article › peer-review
50 Citations (Scopus) -
Transcriptional networks in a rat model for nonalcoholic fatty liver disease: A microarray analysis
Sharma, M. R., Polavarapu, R., Roseman, D., Patel, V., Eaton, E., Kishor, P. B. K. & Nanji, A. A., Dec 2006, In: Experimental and Molecular Pathology. 81, 3, p. 202-210 9 p.Research output: Contribution to journal › Article › peer-review
12 Citations (Scopus) -
2005
Expression of hepatocyte growth factor and its receptor c-met, correlates with severity of pathological injury in experimental alcoholic liver disease.
Lalani, E. N., Poulsom, R., Stamp, G., Fogt, F., Thomas, P. & Nanji, A. A., May 2005, In: International Journal of Molecular Medicine. 15, 5, p. 811-817 7 p.Research output: Contribution to journal › Article › peer-review
12 Citations (Scopus) -
Macrophage migration inhibitory factor expression correlates with inflammatory changes in human chronic hepatitis B infection
Zhang, H. Y., Nanji, A. A., Luk, J. M., Huang, X. R., Lo, C. M., Chen, Y. X., Yuen, S. T., Lan, H. Y. & Lau, G. K. K., Jun 2005, In: Liver International. 25, 3, p. 571-579 9 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
2004
Alcoholic liver injury in the rat is associated with reduced expression of peroxisome proliferator-α (PPARα)-regulated genes and is ameliorated by PPARα activation
Nanji, A. A., Dannenberg, A. J., Jokelainen, K. & Bass, N. M., Jul 2004, In: Journal of Pharmacology and Experimental Therapeutics. 310, 1, p. 417-424 8 p.Research output: Contribution to journal › Article › peer-review
102 Citations (Scopus) -
Animal models of nonalcoholic fatty liver disease and steatohepatitis
Nanji, A. A., Aug 2004, In: Clinics in Liver Disease. 8, 3, p. 559-574 16 p.Research output: Contribution to journal › Review article › peer-review
65 Citations (Scopus) -
Another animal model for nonalcoholic steatohepatitis: How close to the human condition?
Nanji, A. A., Mar 2004, In: American Journal of Clinical Nutrition. 79, 3, p. 350-351 2 p.Research output: Contribution to journal › Editorial › peer-review
Open Access8 Citations (Scopus) -
Decreased proteasome activity is associated with increased severity of liver pathology and oxidative stress in experimental alcoholic liver disease
Donohue, T. M., Kharbanda, K. K., Casey, C. A. & Nanji, A. A., Aug 2004, In: Alcoholism: Clinical and Experimental Research. 28, 8, p. 1257-1263 7 p.Research output: Contribution to journal › Article › peer-review
35 Citations (Scopus) -
Green tea polyphenols prevent toxin-induced hepatotoxicity in mice by down-regulating inducible nitric oxide-derived prooxidants
Chen, J. H., Tipoe, G. L., Liong, E. C., So, H. S. H., Leung, K. M., Tom, W. M., Fung, P. C. W. & Nanji, A. A., Sept 2004, In: American Journal of Clinical Nutrition. 80, 3, p. 742-751 10 p.Research output: Contribution to journal › Article › peer-review
Open Access157 Citations (Scopus) -
Impaired hepatocyte regeneration in toll-like receptor 4 mutant mice
Su, G. L., Wang, S. C., Aminlari, A., Tipoe, G. L., Steinstraesser, L. & Nanji, A., May 2004, In: Digestive Diseases and Sciences. 49, 5, p. 843-849 7 p.Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus) -
Liver asialoglycoprotein receptor levels correlate with severity of alcoholic liver damage in rats
Casey, C. A., McVicker, B. L., Donohue, T. M., McFarland, M. A., Wiegert, R. L. & Nanji, A. A., Jan 2004, In: Journal of Applied Physiology. 96, 1, p. 76-80 5 p.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
Role of different dietary fatty acids in the pathogenesis of experimental alcoholic liver disease
Nanji, A. A., Aug 2004, In: Alcohol. 34, 1, p. 21-25 5 p.Research output: Contribution to journal › Article › peer-review
77 Citations (Scopus) -
2003
Animal models of alcoholic liver disease - Focus on the intragastric feeding model
Nanji, A. A. & French, S. W., 2003, In: Alcohol Research and Health. 27, 4, p. 325-330 6 p.Research output: Contribution to journal › Review article › peer-review
42 Citations (Scopus) -
Curcumin prevents alcohol-induced liver disease in rats by inhibiting the expression of NF-κB-dependent genes
Nanji, A. A., Jokelainen, K., Tipoe, G. L., Rahemtulla, A., Thomas, P. & Dannenberg, A. J., Feb 1 2003, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 284, 2 47-2, p. G321-G327Research output: Contribution to journal › Article › peer-review
309 Citations (Scopus) -
Induction of CYP3A by ethanol in multiple in vitro and in vivo models
Feierman, D. E., Melinkov, Z. & Nanji, A. A., Jun 1 2003, In: Alcoholism: Clinical and Experimental Research. 27, 6, p. 981-988 8 p.Research output: Contribution to journal › Article › peer-review
53 Citations (Scopus) -
Role of apoptosis in alcoholic liver injury
Ishii, H., Adachi, M., Fernández-Checa, J. C., Cederbaum, A. I., Deaciuc, I. V. & Nanji, A. A., Jul 1 2003, In: Alcoholism: Clinical and Experimental Research. 27, 7, p. 1207-1212 6 p.Research output: Contribution to journal › Article › peer-review
43 Citations (Scopus) -
2002
Pathogenesis of alcoholic liver disease-recent advances
Nanji, A. A., Su, G. L., Laposata, M. & French, S. W., 2002, In: Alcoholism: Clinical and Experimental Research. 26, 5, p. 731-736 6 p.Research output: Contribution to journal › Article › peer-review
38 Citations (Scopus) -
Resolution of chronic hepatitis B and anti-HBs seroconversion in humans by adoptive transfer of immunity to hepatitis B core antigen
Lau, G. K. K., Suri, D., Liang, R., Rigopoulou, E. I., Thomas, M. G., Mullerova, I., Nanji, A., Yuen, S. T., Williams, R. & Naoumov, N. V., 2002, In: Gastroenterology. 122, 3, p. 614-624 11 p.Research output: Contribution to journal › Article › peer-review
161 Citations (Scopus) -
Role of Kupffer cells in alcoholic hepatitis
Nanji, A. A., 2002, In: Alcohol. 27, 1, p. 13-15 3 p.Research output: Contribution to journal › Article › peer-review
42 Citations (Scopus) -
Thymosin-α1 and famciclovir combination therapy activates T-cell response in patients with chronic hepatitis B virus infection in immune-tolerant phase
Lau, G. K. K., Nanji, A., Hou, J., Fong, D. Y. T., Au, W. S., Yuen, S. T., Lin, M., Kung, H. F. & Lam, S. K., 2002, In: Journal of Viral Hepatitis. 9, 4, p. 280-287 8 p.Research output: Contribution to journal › Article › peer-review
35 Citations (Scopus) -
2001
Alcoholic liver disease and apoptosis
Casey, C. A., Nanji, A., Cederbaum, A. I., Adachi, M. & Takahashi, T., 2001, In: Alcoholism: Clinical and Experimental Research. 25, 5 SUPPL., p. 49S-53SResearch output: Contribution to journal › Article › peer-review
43 Citations (Scopus) -
Arginine reverses ethanol-induced inflammatory and fibrotic changes in liver despite continued ethanol administration
Nanji, A. A., Jokelainen, K., Lau, G. K. K., Rahemtulla, A., Tipoe, G. L., Polavarapu, R. & Lalani, E. N., 2001, In: Journal of Pharmacology and Experimental Therapeutics. 299, 3, p. 832-839 8 p.Research output: Contribution to journal › Article › peer-review
68 Citations (Scopus) -
Dietary saturated fatty acids reverse inflammatory and fibrotic changes in rat liver despite continued ethanol administration
Nanji, A. A., Jokelainen, K., Tipoe, G. L., Rahemtulla, A. & Dannenberg, A. J., 2001, In: Journal of Pharmacology and Experimental Therapeutics. 299, 2, p. 638-644 7 p.Research output: Contribution to journal › Article › peer-review
99 Citations (Scopus) -
Downregulation of nuclear sex steroid receptor activity correlates with severity of alcoholic liver injury
Eagon, P. K., Elm, M. S., Tadic, S. D. & Nanji, A. A., 2001, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 281, 2 44-2, p. G342-G349Research output: Contribution to journal › Article › peer-review
11 Citations (Scopus) -
Increased severity of alcoholic liver injury in female rats: Role of oxidative stress, endotoxin, and chemokines
Nanji, A. A., Jokelainen, K., Fotouhinia, M., Rahemtulla, A., Thomas, P., Tipoe, G. L., Grace, L. S. U. & Dannenberg, A. J., 2001, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 281, 6 44-6, p. G1348-G1356Research output: Contribution to journal › Article › peer-review
152 Citations (Scopus)