Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Simon Gebremeskel is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Chemokine signaling pathways in resting and activated Natural Killer T cells
Gebremeskel, S. (PI)
Natural Sciences and Engineering Research Council of Canada
1/1/12 → …
Project: Research project
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5T4-CAR-NKT cell therapy for pediatric rhabdomyosarcoma
Gebremeskel, S. (PI) & Mahoney, D. (CoI)
11/1/17 → 10/31/20
Project: Research project
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NKT cell immunotherapy for breast cancer
Gebremeskel, S. (PI) & Johnston, B. B. (CoI)
5/1/15 → 4/30/18
Project: Research project
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Natural killer T cell immunotherapy combined with IL-15-expressing oncolytic virotherapy and PD-1 blockade mediates pancreatic tumor regression
Nelson, A., Gebremeskel, S., Lichty, B. D. & Johnston, B., Mar 1 2022, In: Journal for ImmunoTherapy of Cancer. 10, 3Research output: Contribution to journal › Article › peer-review
Open Access29 Citations (Scopus) -
Pilot study of jadomycin B pharmacokinetics and anti-tumoral effects in zebrafish larvae and mouse breast cancer xenograft models
McKeown, B. T., Relja, N. J., Hall, S. R., Gebremeskel, S., Macleod, J. M., Veinotte, C. J., Bennett, L. G., Ohlund, L. B., Sleno, L., Jakeman, D. L., Berman, J. N., Johnston, B. & Goralski, K. B., 2022, In: Canadian Journal of Physiology and Pharmacology. 100, 11, p. 1065-1076 12 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
The Inhibitory Receptor Siglec-8 Interacts With FcεRI and Globally Inhibits Intracellular Signaling in Primary Mast Cells Upon Activation
Korver, W., Wong, A., Gebremeskel, S., Negri, G. L., Schanin, J., Chang, K., Leung, J., Benet, Z., Luu, T., Brock, E. C., Luehrsen, K., Xu, A. & Youngblood, B. A., Jan 28 2022, In: Frontiers in Immunology. 13, 833728.Research output: Contribution to journal › Article › peer-review
Open Access24 Citations (Scopus) -
A monoclonal antibody to Siglec-8 suppresses non-allergic airway inflammation and inhibits IgE-independent mast cell activation
Schanin, J., Gebremeskel, S., Korver, W., Falahati, R., Butuci, M., Haw, T. J., Nair, P. M., Liu, G., Hansbro, N. G., Hansbro, P. M., Evensen, E., Brock, E. C., Xu, A., Wong, A., Leung, J., Bebbington, C., Tomasevic, N. & Youngblood, B. A., Mar 2021, In: Mucosal Immunology. 14, 2, p. 366-376 11 p.Research output: Contribution to journal › Article › peer-review
Open Access65 Citations (Scopus) -
Mast Cell and Eosinophil Activation Are Associated With COVID-19 and TLR-Mediated Viral Inflammation: Implications for an Anti-Siglec-8 Antibody
Gebremeskel, S., Schanin, J., Coyle, K. M., Butuci, M., Luu, T., Brock, E. C., Xu, A., Wong, A., Leung, J., Korver, W., Morin, R. D., Schleimer, R. P., Bochner, B. S. & Youngblood, B. A., Mar 10 2021, In: Frontiers in Immunology. 12, 650331.Research output: Contribution to journal › Article › peer-review
Open Access95 Citations (Scopus)
Press/Media
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Allakos Declares Multiple Presentations on Eosinophil and Mast Cell-Driven Diseases
6/1/20
1 item of Media coverage
Press/Media: Research
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Allakos Announces Multiple Presentations Related to Eosinophil and Mast Cell-Driven Diseases at the Digital EAACI Annual Congress 2020 Nasdaq:ALLK
5/21/20
1 item of Media coverage
Press/Media: Research
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Allakos Announces Multiple Presentations Related to Eosinophil and Mast Cell-Driven Diseases at the Digital EAACI Annual Congress 2020
5/21/20
13 items of Media coverage
Press/Media: Research
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Allakos Announces Multiple Presentations Related to Eosinophil and Mast Cell-Driven Diseases at the Digital EAACI Annual Congress 2020
5/21/20
1 item of Media coverage
Press/Media: Research