Abstract
The authors report a case of 'black cornea' secondary to topical epinephrine therapy and present the biochemical analysis of the lesion. The formed pigment is a melanin and not the intermediate substance, adrenochrome, as has been previously reported. The pathogenesis of melanin deposition is reviewed and a hypothesis of epinephrine melanin binding is suggested.
| Original language | English |
|---|---|
| Pages (from-to) | 336-340 |
| Number of pages | 5 |
| Journal | Canadian Journal of Ophthalmology |
| Volume | 11 |
| Issue number | 4 |
| Publication status | Published - 1976 |
| Externally published | Yes |
ASJC Scopus Subject Areas
- Ophthalmology