A Miniature 16-element Endoscopic Histotripsy Transducer with Electronically Steerable Focus

Matthew Mallay; Jeffery Woodacre; Taha Take; Emily Napier; Sandra Gorgey; Jeremy Brown

doi:10.1109/ULTSYM.2019.8926086

A Miniature 16-element Endoscopic Histotripsy Transducer with Electronically Steerable Focus

Matthew Mallay, Jeffery Woodacre, Taha Take, Emily Napier, Sandra Gorgey, Jeremy Brown

Medicine

Medicine

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

A 5 mm by 5 mm 16-element histotripsy transducer was built and tested using a lens bonded to an air-backed 1-3 piezoelectric composite. The transducer was driven by a custom designed 16 channel pulse generator. Both aluminum and methacrylate photopolymer (resin) lens designs were modelled using a COMSOL FEM model. A resin lens was 3D printed and used to fabricate a transducer array with a focus that could be steered over a greater area than the aluminum lens design. The resin lens transducer had a peak negative pressure trend of 5.7 MPa/100 V. The -3 dB focal length and width were 1.94 mm and 0.30 mm. A pulse sequence cycling through 5 foci spaced within a 1.5 mm square was used to ablate ex vivo rat brain tissue through shock scattering cavitation near the surface.

Original language	English
Title of host publication	2019 IEEE International Ultrasonics Symposium, IUS 2019
Publisher	IEEE Computer Society
Pages	1797-1800
Number of pages	4
ISBN (Electronic)	9781728145969
DOIs	https://doi.org/10.1109/ULTSYM.2019.8926086
Publication status	Published - Oct 2019
Event	2019 IEEE International Ultrasonics Symposium, IUS 2019 - Glasgow, United Kingdom Duration: Oct 6 2019 → Oct 9 2019

Publication series

Name	IEEE International Ultrasonics Symposium, IUS
Volume	2019-October
ISSN (Print)	1948-5719
ISSN (Electronic)	1948-5727

Conference

Conference	2019 IEEE International Ultrasonics Symposium, IUS 2019
Country/Territory	United Kingdom
City	Glasgow
Period	10/6/19 → 10/9/19

Bibliographical note

Publisher Copyright:
© 2019 IEEE.

ASJC Scopus Subject Areas

Acoustics and Ultrasonics

Access to Document

10.1109/ULTSYM.2019.8926086

Cite this

Mallay, M., Woodacre, J., Take, T., Napier, E., Gorgey, S., & Brown, J. (2019). A Miniature 16-element Endoscopic Histotripsy Transducer with Electronically Steerable Focus. In 2019 IEEE International Ultrasonics Symposium, IUS 2019 (pp. 1797-1800). Article 8926086 (IEEE International Ultrasonics Symposium, IUS; Vol. 2019-October). IEEE Computer Society. https://doi.org/10.1109/ULTSYM.2019.8926086

A Miniature 16-element Endoscopic Histotripsy Transducer with Electronically Steerable Focus. / Mallay, Matthew; Woodacre, Jeffery; Take, Taha et al.
2019 IEEE International Ultrasonics Symposium, IUS 2019. IEEE Computer Society, 2019. p. 1797-1800 8926086 (IEEE International Ultrasonics Symposium, IUS; Vol. 2019-October).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Mallay, M, Woodacre, J, Take, T, Napier, E, Gorgey, S & Brown, J 2019, A Miniature 16-element Endoscopic Histotripsy Transducer with Electronically Steerable Focus. in 2019 IEEE International Ultrasonics Symposium, IUS 2019., 8926086, IEEE International Ultrasonics Symposium, IUS, vol. 2019-October, IEEE Computer Society, pp. 1797-1800, 2019 IEEE International Ultrasonics Symposium, IUS 2019, Glasgow, United Kingdom, 10/6/19. https://doi.org/10.1109/ULTSYM.2019.8926086

@inproceedings{3ae751dc0c85456296b47cf5fdcc9d09,

title = "A Miniature 16-element Endoscopic Histotripsy Transducer with Electronically Steerable Focus",

abstract = "A 5 mm by 5 mm 16-element histotripsy transducer was built and tested using a lens bonded to an air-backed 1-3 piezoelectric composite. The transducer was driven by a custom designed 16 channel pulse generator. Both aluminum and methacrylate photopolymer (resin) lens designs were modelled using a COMSOL FEM model. A resin lens was 3D printed and used to fabricate a transducer array with a focus that could be steered over a greater area than the aluminum lens design. The resin lens transducer had a peak negative pressure trend of 5.7 MPa/100 V. The -3 dB focal length and width were 1.94 mm and 0.30 mm. A pulse sequence cycling through 5 foci spaced within a 1.5 mm square was used to ablate ex vivo rat brain tissue through shock scattering cavitation near the surface.",

author = "Matthew Mallay and Jeffery Woodacre and Taha Take and Emily Napier and Sandra Gorgey and Jeremy Brown",

note = "Publisher Copyright: {\textcopyright} 2019 IEEE.; 2019 IEEE International Ultrasonics Symposium, IUS 2019 ; Conference date: 06-10-2019 Through 09-10-2019",

year = "2019",

month = oct,

doi = "10.1109/ULTSYM.2019.8926086",

language = "English",

series = "IEEE International Ultrasonics Symposium, IUS",

publisher = "IEEE Computer Society",

pages = "1797--1800",

booktitle = "2019 IEEE International Ultrasonics Symposium, IUS 2019",

address = "United States",

}

TY - GEN

T1 - A Miniature 16-element Endoscopic Histotripsy Transducer with Electronically Steerable Focus

AU - Mallay, Matthew

AU - Woodacre, Jeffery

AU - Take, Taha

AU - Napier, Emily

AU - Gorgey, Sandra

AU - Brown, Jeremy

PY - 2019/10

Y1 - 2019/10

N2 - A 5 mm by 5 mm 16-element histotripsy transducer was built and tested using a lens bonded to an air-backed 1-3 piezoelectric composite. The transducer was driven by a custom designed 16 channel pulse generator. Both aluminum and methacrylate photopolymer (resin) lens designs were modelled using a COMSOL FEM model. A resin lens was 3D printed and used to fabricate a transducer array with a focus that could be steered over a greater area than the aluminum lens design. The resin lens transducer had a peak negative pressure trend of 5.7 MPa/100 V. The -3 dB focal length and width were 1.94 mm and 0.30 mm. A pulse sequence cycling through 5 foci spaced within a 1.5 mm square was used to ablate ex vivo rat brain tissue through shock scattering cavitation near the surface.

AB - A 5 mm by 5 mm 16-element histotripsy transducer was built and tested using a lens bonded to an air-backed 1-3 piezoelectric composite. The transducer was driven by a custom designed 16 channel pulse generator. Both aluminum and methacrylate photopolymer (resin) lens designs were modelled using a COMSOL FEM model. A resin lens was 3D printed and used to fabricate a transducer array with a focus that could be steered over a greater area than the aluminum lens design. The resin lens transducer had a peak negative pressure trend of 5.7 MPa/100 V. The -3 dB focal length and width were 1.94 mm and 0.30 mm. A pulse sequence cycling through 5 foci spaced within a 1.5 mm square was used to ablate ex vivo rat brain tissue through shock scattering cavitation near the surface.

UR - http://www.scopus.com/inward/record.url?scp=85077597627&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85077597627&partnerID=8YFLogxK

U2 - 10.1109/ULTSYM.2019.8926086

DO - 10.1109/ULTSYM.2019.8926086

M3 - Conference contribution

AN - SCOPUS:85077597627

T3 - IEEE International Ultrasonics Symposium, IUS

SP - 1797

EP - 1800

BT - 2019 IEEE International Ultrasonics Symposium, IUS 2019

PB - IEEE Computer Society

T2 - 2019 IEEE International Ultrasonics Symposium, IUS 2019

Y2 - 6 October 2019 through 9 October 2019

ER -

A Miniature 16-element Endoscopic Histotripsy Transducer with Electronically Steerable Focus

Abstract

Publication series

Conference

Bibliographical note

ASJC Scopus Subject Areas

Access to Document

Other files and links

Fingerprint

Cite this