Abstract
A modification of the urine osmolal gap was evaluated as an estimate of urine [NH4]. We proposed that: (Equation Present) Spot urine samples were collected from normal volunteers and from individuals with ketonuria; the modified urine osmolal gap as well as two other previously described estimates of urine [NH+4] were compared with measured urine [NH+4]. There was a significant positive linear correlation between the urine [NH+4] and the modified urine osmolal gap in normal volunteers (r = 0.81; p < 0.01) and in individuals with ketonuria (r = 0.93; p < 0.001). The originally described urine osmolal gap greatly overestimated the urine [NH+4] but also showed a significant correlation. The urine anion gap was not a valid estimate of urine [NH+4] within the range of values measured in our subjects. The modified urine osmolal gap is an improvement over previously described estimates of urine [NH+4] and can be used as a single calculation in place of the other two.
Original language | English |
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Pages (from-to) | 359-362 |
Number of pages | 4 |
Journal | American Journal of Nephrology |
Volume | 10 |
Issue number | 5 |
DOIs | |
Publication status | Published - 1990 |
Externally published | Yes |
ASJC Scopus Subject Areas
- Nephrology
PubMed: MeSH publication types
- Comparative Study
- Journal Article