A study of parental age effects on the occurrence of fresh mutations for the Apert syndrome

J. DAVID ERICKSON, M. MICHAEL COHEN

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36 Citations (Scopus)

Abstract

A sample of 44 patients with the Apert syndrome was analysed for parental age effects on the occurrence of fresh mutations by using two conceptually similar techniques, one proposed by Smith (1972) and the other devised for the purposes of this study. The results of both analyses confirmed the parental age effect reported by Blank (1960), and was probably due solely to increased paternal age.

Original languageEnglish
Pages (from-to)89-96
Number of pages8
JournalAnnals of Human Genetics
Volume38
Issue number1
DOIs
Publication statusPublished - Jul 1974
Externally publishedYes

ASJC Scopus Subject Areas

  • Genetics
  • Genetics(clinical)

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