Abstract
The effect of two naturally occurring opiate peptides, methionine-enkephalin (MET-ENK) and leucine-enkephalin (LEU-ENK) on the in vivo release of acetylcholine (ACh) from the cerebral cortex was investigated in the rat. It is concluded that MET-ENK and LEU-ENK influence the cortical release of ACh by a selective action on central opiate receptors, and suggested that one of their physiological roles may be modulated of activity in the central cholinergic pathways.
| Original language | English |
|---|---|
| Pages (from-to) | No. 356 |
| Journal | Pharmacologist |
| Volume | 19 |
| Issue number | 2 |
| Publication status | Published - 1977 |
| Externally published | Yes |
ASJC Scopus Subject Areas
- Pharmacology, Toxicology and Pharmaceutics(all)