Acute poststreptococcal glomerulonephritis in Maracaibo. II. Studies on the incidence, nature, and significance of circulatiing anti-immunoglobulins

R. M. McIntosh, D. Rabideau, J. E. Allen, R. Garcia, L. Rubio, R. I. Carr, B. Rodriguez-Iturbe

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

Antiglobulins were measured in the sera of 82 patients with acute poststreptococcal glomerulonephritis and correlated with C1q binding activity, serum levels of immunoglobulins and C3, site of infection, antibody titres to streptococcal enzymes, and the duration of the nephritis and interval from infection. Raised serum antiglobulins were found in 89.2% of the patients. In addition, raised titres were detected at any time during the course of the disease and very early after streptococcal infection. The finding of antiglobulins soon after the infection suggests the possibility that they appear as a primary event in the disease.

Original languageEnglish
Pages (from-to)257-261
Number of pages5
JournalUnknown Journal
Volume38
Issue number3
DOIs
Publication statusPublished - 1979

ASJC Scopus Subject Areas

  • Immunology and Allergy
  • Rheumatology
  • Immunology
  • General Biochemistry,Genetics and Molecular Biology

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