TY - JOUR
T1 - Affective Disorders and Mortality
T2 - A General Population Study
AU - Murphy, Jane M.
AU - Monson, Richard R.
AU - Olivier, Donald C.
AU - Sobol, Arthur M.
AU - Leighton, Alexander H.
PY - 1987/5
Y1 - 1987/5
N2 - A 16-year prospective study of a general population sample indicates that those who had reported a depression and/or anxiety disorder at baseline experienced 1.5 times the number of deaths expected on the basis of rates for a large reference population. As part of the Stirling County Study (Canada), the information was gathered from 1003 adults through structured interviews and was analyzed by means of a diagnostic computer program. The risk for mortality was assessed using external and internal standards, controlling for the effects of age and sex as well as for the presence of self-reported physical disorders at baseline. Increased risk was found to be significantly associated with affective but not physical disorders and with depression but not generalized anxiety. When this evidence about mortality was combined with information about subsequent psychiatric morbidity among survivors, 82% of those who were depressed at baseline had a poor outcome.
AB - A 16-year prospective study of a general population sample indicates that those who had reported a depression and/or anxiety disorder at baseline experienced 1.5 times the number of deaths expected on the basis of rates for a large reference population. As part of the Stirling County Study (Canada), the information was gathered from 1003 adults through structured interviews and was analyzed by means of a diagnostic computer program. The risk for mortality was assessed using external and internal standards, controlling for the effects of age and sex as well as for the presence of self-reported physical disorders at baseline. Increased risk was found to be significantly associated with affective but not physical disorders and with depression but not generalized anxiety. When this evidence about mortality was combined with information about subsequent psychiatric morbidity among survivors, 82% of those who were depressed at baseline had a poor outcome.
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U2 - 10.1001/archpsyc.1987.01800170095012
DO - 10.1001/archpsyc.1987.01800170095012
M3 - Article
C2 - 3555383
AN - SCOPUS:0023188176
SN - 0003-990X
VL - 44
SP - 473
EP - 480
JO - Archives of General Psychiatry
JF - Archives of General Psychiatry
IS - 5
ER -
