Age at onset in bipolar disorder: Investigation of the role of TaqIA polymorphism of DRD2 gene in a Sardinian sample

A. Squassina; M. Manchia; M. Costa; C. Chillotti; R. Ardau; M. Del Zompo; G. Severino

doi:10.1016/j.eurpsy.2010.09.013

Age at onset in bipolar disorder: Investigation of the role of TaqIA polymorphism of DRD2 gene in a Sardinian sample

A. Squassina, M. Manchia, M. Costa, C. Chillotti, R. Ardau, M. Del Zompo, G. Severino

Medicine

Medicine

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

Bipolar disorder (BD) is a highly heterogeneous and heritable psychiatric illness. Age at onset has been shown to be a powerful tool for dissecting both the phenotypic and genetic complexity of BD. In this article, we present findings from an association study between the DRD2 TaqIA polymorphism and age at onset, showing that both alleles and genotypes at this locus associate with early onset BD.

Original language	English
Pages (from-to)	141-143
Number of pages	3
Journal	European Psychiatry
Volume	26
Issue number	3
DOIs	https://doi.org/10.1016/j.eurpsy.2010.09.013
Publication status	Published - Apr 2011

Bibliographical note

Funding Information:
This work was partly supported by the Regional Councillorship of Health, “Regione Autonoma della Sardegna” with a grant dedicated to Drug Information and surveillance Projects. A. Squassina is supported by a Grant from “Regione Autonoma della Sardegna”, and the European Social Fund (ESF), LR7 2007. M. Manchia is supported by the Sobey Fellowship, Department of Psychiatry, Dalhousie University, NS, Canada.

ASJC Scopus Subject Areas

Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.eurpsy.2010.09.013

Cite this

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abstract = "Bipolar disorder (BD) is a highly heterogeneous and heritable psychiatric illness. Age at onset has been shown to be a powerful tool for dissecting both the phenotypic and genetic complexity of BD. In this article, we present findings from an association study between the DRD2 TaqIA polymorphism and age at onset, showing that both alleles and genotypes at this locus associate with early onset BD.",

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AU - Chillotti, C.

AU - Ardau, R.

AU - Del Zompo, M.

AU - Severino, G.

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Age at onset in bipolar disorder: Investigation of the role of TaqIA polymorphism of DRD2 gene in a Sardinian sample

Abstract

Bibliographical note

ASJC Scopus Subject Areas

UN SDGs

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