Allergic Reactions to Hyaluronidase

Leon S. Kind; Suzanne Roffler

doi:10.3181/00379727-106-26458

Allergic Reactions to Hyaluronidase

Leon S. Kind, Suzanne Roffler

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

It has been demonstrated by hemagglutination inhibition tests as well as by induction of anaphylactic shock that a commercial hyaluronidase preparation contained a small but appreciable amount of bovine serum proteins. In view of the known allergenic properties of such impurities it is suggested that skin tests with bovine serum precede administration of hyaluronidase.

Original language	English
Pages (from-to)	734-735
Number of pages	2
Journal	Experimental Biology and Medicine
Volume	106
Issue number	4
DOIs	https://doi.org/10.3181/00379727-106-26458
Publication status	Published - Apr 1961
Externally published	Yes

Bibliographical note

Funding Information:
This investigation was aided by research grants from Nat. Inst. of Health, U.S.P.H.S.

ASJC Scopus Subject Areas

General Biochemistry,Genetics and Molecular Biology

PubMed: MeSH publication types

Journal Article

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10.3181/00379727-106-26458

Cite this

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title = "Allergic Reactions to Hyaluronidase",

abstract = "It has been demonstrated by hemagglutination inhibition tests as well as by induction of anaphylactic shock that a commercial hyaluronidase preparation contained a small but appreciable amount of bovine serum proteins. In view of the known allergenic properties of such impurities it is suggested that skin tests with bovine serum precede administration of hyaluronidase.",

author = "Kind, {Leon S.} and Suzanne Roffler",

note = "Funding Information: This investigation was aided by research grants from Nat. Inst. of Health, U.S.P.H.S.",

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AU - Kind, Leon S.

AU - Roffler, Suzanne

N1 - Funding Information: This investigation was aided by research grants from Nat. Inst. of Health, U.S.P.H.S.

PY - 1961/4

Y1 - 1961/4

N2 - It has been demonstrated by hemagglutination inhibition tests as well as by induction of anaphylactic shock that a commercial hyaluronidase preparation contained a small but appreciable amount of bovine serum proteins. In view of the known allergenic properties of such impurities it is suggested that skin tests with bovine serum precede administration of hyaluronidase.

AB - It has been demonstrated by hemagglutination inhibition tests as well as by induction of anaphylactic shock that a commercial hyaluronidase preparation contained a small but appreciable amount of bovine serum proteins. In view of the known allergenic properties of such impurities it is suggested that skin tests with bovine serum precede administration of hyaluronidase.

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U2 - 10.3181/00379727-106-26458

DO - 10.3181/00379727-106-26458

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JO - Experimental Biology and Medicine

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Allergic Reactions to Hyaluronidase

Abstract

Bibliographical note

ASJC Scopus Subject Areas

PubMed: MeSH publication types

Access to Document

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