An individualized approach to tracking and treating Alzheimers disease

There can be substantial variation in the expression of Alzheimers disease. Patients vary in who is affected (e.g., education, age at onset), in how they are affected (e.g., neuropathological profile, comorbidities), and in when they present (i.e., stage of illness). Even people with similar starting profiles can have dramatically different courses. For these reasons, tracking disease progression in individuals and the effects of treatment on them can be challenging. This variability further complicates the difficulty of dementias high dimensionalityAlzheimers disease affects many aspects of cognition, function, and behavior.