An isolated mammalian brainstem-spinal cord preparation suitable for the investigation of descending control of motor activity

J. Bagust; Melanie E.M. Kelly; G. A. Kerkut

doi:10.1016/0006-8993(85)91539-2

An isolated mammalian brainstem-spinal cord preparation suitable for the investigation of descending control of motor activity

J. Bagust, Melanie E.M. Kelly, G. A. Kerkut

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

An in vitro, hemisected brainstem-spinal cord preparation which allows bulbo-spinal interactions to be investigated, has been developed using 25-33 g golden hamsters. Spinal reflexes showing both monosynaptic and polysynaptic components were recorded from the lumbar ventral roots following stimulation of the corresponding dorsal roots. Trains of conditioning stimuli delivered to the caudal region of the medulla caused inhibition of the monosynaptic component and potentiation of the polysynaptic component of the spinal reflex.

Original language	English
Pages (from-to)	370-374
Number of pages	5
Journal	Brain Research
Volume	327
Issue number	1-2
DOIs	https://doi.org/10.1016/0006-8993(85)91539-2
Publication status	Published - Feb 18 1985
Externally published	Yes

Bibliographical note

Funding Information:
M.K. is funded by the SERC.

ASJC Scopus Subject Areas

General Neuroscience
Molecular Biology
Clinical Neurology
Developmental Biology

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10.1016/0006-8993(85)91539-2

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abstract = "An in vitro, hemisected brainstem-spinal cord preparation which allows bulbo-spinal interactions to be investigated, has been developed using 25-33 g golden hamsters. Spinal reflexes showing both monosynaptic and polysynaptic components were recorded from the lumbar ventral roots following stimulation of the corresponding dorsal roots. Trains of conditioning stimuli delivered to the caudal region of the medulla caused inhibition of the monosynaptic component and potentiation of the polysynaptic component of the spinal reflex.",

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AU - Kerkut, G. A.

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Y1 - 1985/2/18

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AB - An in vitro, hemisected brainstem-spinal cord preparation which allows bulbo-spinal interactions to be investigated, has been developed using 25-33 g golden hamsters. Spinal reflexes showing both monosynaptic and polysynaptic components were recorded from the lumbar ventral roots following stimulation of the corresponding dorsal roots. Trains of conditioning stimuli delivered to the caudal region of the medulla caused inhibition of the monosynaptic component and potentiation of the polysynaptic component of the spinal reflex.

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An isolated mammalian brainstem-spinal cord preparation suitable for the investigation of descending control of motor activity

Abstract

Bibliographical note

ASJC Scopus Subject Areas

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