Abstract
Titin is a giant filamentous protein of striated muscle composed of > 300 immunoglobulin-like domains linked in tandem. Here, we demonstrate that a six-immunoglobulin fragment of titin carrying a poly-histidine tag forms a protein "brush" on liposomes containing metallochelating lipids. These specimens might allow the direct visualization by cryo-EM of frozen hydrated and unstained titin chains with preserved architectural features.
Original language | English |
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Pages (from-to) | 178-179 |
Number of pages | 2 |
Journal | Journal of Bioscience and Bioengineering |
Volume | 112 |
Issue number | 2 |
DOIs | |
Publication status | Published - Aug 2011 |
ASJC Scopus Subject Areas
- Biotechnology
- Bioengineering
- Applied Microbiology and Biotechnology