Butyrylcholinesterase and cognitive function

Research output: Contribution to journalArticlepeer-review

28 Citations (Scopus)

Abstract

Butyrylcholinesterase (BuChE) is expressed in brain structures involved in cognition, but the effect of selective BuChE inhibitors on human cognitive function is unknown. We report a patient whose cognitive function deteriorated following a reduction and improved following reinstitution of ethopropazine, a selective BuChE inhibitor. We suggest that, because neurons expressing BuChE may be involved in cognition, there is merit to further evaluation of selective BuChE inhibitors in treating cognitive dysfunction.

Original languageEnglish
Pages (from-to)461-464
Number of pages4
JournalInternational Psychogeriatrics
Volume13
Issue number4
DOIs
Publication statusPublished - 2001

ASJC Scopus Subject Areas

  • Clinical Psychology
  • Gerontology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health

PubMed: MeSH publication types

  • Case Reports
  • Journal Article
  • Research Support, Non-U.S. Gov't

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