Comparative actions of β-endorphin-like peptides in spinal antinociception tests

K. Jhamandas, M. Hong

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Comparative spinal actions of β-endorphin1-31 (B-EP1-31) and its shorter fragments were examined in antinociception tests. β-EP1-31) produced potent antinociception, β-EP1-27 demonstrated weaker activity, and β-EP1-26 was inactive. B-EP1-27 did not antagonize morphine-induced spinal antinociception.

Original languageEnglish
Title of host publicationNew leads in opioid research
Subtitle of host publicationproceedings of the International Narcotics Research Conference. ICS914
EditorsJ.M. Van Ree, A.H. Mulder, V.M. Wiegant, T.B. Van Wimersma Greidanus, J.M. Van Ree, A.H. Mulder, V.M. Wiegant, T.B. Van Wimersma Greidanus
PublisherElsevier Science Publishers B.V.
Pages35
Number of pages1
ISBN (Print)044481213X
Publication statusPublished - 1990
Externally publishedYes
EventThe International Narcotics Research Conference -
Duration: Jul 8 1989Jul 13 1989

Publication series

NameNew leads in opioid research: proceedings of the International Narcotics Research Conference. ICS914

Conference

ConferenceThe International Narcotics Research Conference
Period7/8/897/13/89

ASJC Scopus Subject Areas

  • General Medicine

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