Abstract
Acetylcholine released from the visual and sensorimotor cortices was collected in awake rabbits while they were responding for water reinforcement under one of four behavioural paradigms. Acetylcholine release from both sites was found to increase over baseline levels in all behavioural conditions. This was interpreted as due to the diffuse cholinergic input to the cortex from the reticular formation. However, in one condition a significantly greater increase was observed from sensorimotor cortex alone. This supports the existence of a second, more specific cholinergic component in the cortex.
| Original language | English |
|---|---|
| Pages (from-to) | 683-690 |
| Number of pages | 8 |
| Journal | Life Sciences |
| Volume | 16 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Mar 1 1975 |
Bibliographical note
Funding Information:This work was supported by a grant from the Medical Research Council
ASJC Scopus Subject Areas
- General Biochemistry,Genetics and Molecular Biology
- Pharmacology, Toxicology and Pharmaceutics(all)
PubMed: MeSH publication types
- Journal Article
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Rasmusson, D., & Szerb, J. C. (1975). Cortical acetylcholine release during operant behaviour in rabbits. Life Sciences, 16(5), 683-690. https://doi.org/10.1016/0024-3205(75)90345-8