COVID-19 vaccine uptake and intention during pregnancy in Canada

Laura Reifferscheid, Emmanuel Marfo, Ali Assi, Eve Dubé, Noni E. MacDonald, Samantha B. Meyer, Julie A. Bettinger, S. Michelle Driedger, Joan Robinson, Manish Sadarangani, Sarah E. Wilson, Karen Benzies, Samuel Lemaire-Paquette, Arnaud Gagneur, Shannon E. MacDonald

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)

Abstract

Objective: To investigate COVID-19 vaccine uptake and intent among pregnant people in Canada, and determine associated factors. Methods: We conducted a national cross-sectional survey among pregnant people from May 28 through June 7, 2021 (n = 193). Respondents completed a questionnaire to determine COVID-19 vaccine acceptance (defined as either received or intend to receive a COVID-19 vaccine during pregnancy), factors associated with vaccine acceptance, and rationale for accepting/not accepting the vaccine. Results: Of 193 respondents, 57.5% (n = 111) reported COVID-19 vaccine acceptance. Among those who did not accept the vaccine, concern over vaccine safety was the most commonly cited reason (90.1%, n = 73), and 81.7% (n = 67) disagreed with receiving a vaccine that had not been tested in pregnant people. Confidence in COVID-19 vaccine safety (aOR 16.72, 95% CI: 7.22, 42.39), Indigenous self-identification (aOR 11.59, 95% CI: 1.77, 117.18), and employment in an occupation at high risk for COVID-19 exposure excluding healthcare (aOR 4.76, 95% CI: 1.32, 18.60) were associated with vaccine acceptance. Perceived personal risk of COVID-19 disease was not associated with vaccine acceptance in the multivariate model. Conclusion: Vaccine safety is a primary concern for this population. Safety information should be communicated to this population as it emerges, along with clear messaging on the benefits of vaccination, as disease risk is either poorly understood or poorly valued in this population.

Original languageEnglish
JournalCanadian Journal of Public Health
DOIs
Publication statusAccepted/In press - 2022

Bibliographical note

Funding Information:
This study was funded by the Canadian Institutes of Health Research (CIHR).

Funding Information:
MS has been an investigator on projects funded by GlaxoSmithKline, Merck, Pfizer, Sanofi-Pasteur, Seqirus, Symvivo, and VBI Vaccines. All funds have been paid to his institute, and he has not received any personal payments.

Funding Information:
This research is part of a larger project conducted by the COVImm study team. The team acknowledges the Applied Immunization (AImm) Research Program team members Robin Humble and Hannah Sell, who provided editorial input, and Dr. Deshayne Fell, who provided expertise on COVID-19 vaccination recommendations for pregnant people. MS is supported via salary awards from the BC Children’s Hospital Foundation, the Canadian Child Health Clinician Scientist Program, and the Michael Smith Foundation for Health Research.

Publisher Copyright:
© 2022, The Author(s).

ASJC Scopus Subject Areas

  • Public Health, Environmental and Occupational Health

PubMed: MeSH publication types

  • Journal Article
  • Research Support, Non-U.S. Gov't

Fingerprint

Dive into the research topics of 'COVID-19 vaccine uptake and intention during pregnancy in Canada'. Together they form a unique fingerprint.

Cite this