Daily variation in active glycogen phosphorylase patches in the molecular layer of rat dentate gyrus

Carolyn Harley, Benjamin Rusak

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)

Abstract

A larger number of discrete patches of active glycogen phosphorylase (αGP) were found in the molecular layer of the hippocampal dentate gyrus in rats sacrifice during the daily dark phase ( x ̄ = 28.7/section) than during the light phase ( x ̄ = 7.8/section). Light-dark differences in the patterns of αGP may reflect circadian differences in metabolic demand in the hippocampus. Patch sizes were consistent with increased activation of single astrocytes or perisynaptic astrocyte clusters by focal input at night.

Original languageEnglish
Pages (from-to)310-317
Number of pages8
JournalBrain Research
Volume626
Issue number1-2
DOIs
Publication statusPublished - Oct 29 1993

Bibliographical note

Funding Information:
The authors wish to acknowledge the excellent technical contribution of Donna Goguen and Krista Babstock to this project. This research was supported by NSERC grants to C.H. (A9791) and B.R. (A0305).

ASJC Scopus Subject Areas

  • General Neuroscience
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

PubMed: MeSH publication types

  • Journal Article
  • Research Support, Non-U.S. Gov't

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Harley, C., & Rusak, B. (1993). Daily variation in active glycogen phosphorylase patches in the molecular layer of rat dentate gyrus. Brain Research, 626(1-2), 310-317. https://doi.org/10.1016/0006-8993(93)90593-C