TY - GEN
T1 - Detection of acute myocardial ischemia by vessel-specific leads derived from the 12-lead electrocardiogram
AU - Wang, J. Y.
AU - Mirmoghisi, M.
AU - Warren, J. W.
AU - Wagner, G. S.
AU - Horáček, B. M.
PY - 2007
Y1 - 2007
N2 - Our aim was to enhance diagnostic performance of ACC/ESC STEMI criteria based on 12-lead ECG by using criteria from 3 derived vessel-specific leads (VSLs). Study data consisted of 12-lead ECGs acquired during angioplasty-induced ischemic episodes due to balloon inflation in, respectively, LAD (n = 35), RCA (n = 47), and LCx (n = 17) coronary arteries. Three VSLs were derived from 12-lead ECG by previously developed lead transformations. We found that the detection of ischemic state, in any vessel, by means of the ACC/ESC criteria achieved the SE/SP of 60/96% in the total population, whereas in subgroups sorted by vessel SE/SP were 74/97% for LAD, 60/94% for RCA, and 36/100% for LCx. With derived VSLs at 110 μV threshold we achieved in total population SE/SP 84/93% and in subgroups 97/92% for LAD, 77/92% for RCA and 77/100% for LCx. Thus it appears that VSLs can markedly improve detection of ischemia, especially that caused by LCx artery occlusion.
AB - Our aim was to enhance diagnostic performance of ACC/ESC STEMI criteria based on 12-lead ECG by using criteria from 3 derived vessel-specific leads (VSLs). Study data consisted of 12-lead ECGs acquired during angioplasty-induced ischemic episodes due to balloon inflation in, respectively, LAD (n = 35), RCA (n = 47), and LCx (n = 17) coronary arteries. Three VSLs were derived from 12-lead ECG by previously developed lead transformations. We found that the detection of ischemic state, in any vessel, by means of the ACC/ESC criteria achieved the SE/SP of 60/96% in the total population, whereas in subgroups sorted by vessel SE/SP were 74/97% for LAD, 60/94% for RCA, and 36/100% for LCx. With derived VSLs at 110 μV threshold we achieved in total population SE/SP 84/93% and in subgroups 97/92% for LAD, 77/92% for RCA and 77/100% for LCx. Thus it appears that VSLs can markedly improve detection of ischemia, especially that caused by LCx artery occlusion.
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U2 - 10.1109/CIC.2007.4745481
DO - 10.1109/CIC.2007.4745481
M3 - Conference contribution
AN - SCOPUS:62249196351
SN - 9781424425334
T3 - Computers in Cardiology
SP - 301
EP - 304
BT - Computers in Cardiology 2007, CAR 2007
T2 - Computers in Cardiology 2007, CAR 2007
Y2 - 30 September 2007 through 3 October 2007
ER -