Difficulty accessing syringes mediates the relationship between methamphetamine use and syringe sharing among young injection drug users

Brandon D.L. Marshall; Jean A. Shoveller; Evan Wood; Thomas L. Patterson; Thomas Kerr

doi:10.1007/s10461-010-9876-8

Difficulty accessing syringes mediates the relationship between methamphetamine use and syringe sharing among young injection drug users

Brandon D.L. Marshall, Jean A. Shoveller, Evan Wood, Thomas L. Patterson, Thomas Kerr

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

Injection drug users (IDU) who use methamphetamine (MA) are at an increased risk of HIV infection due to engagement in injection-related risk behavior including syringe sharing. In this cohort study of young IDU aged 18-30, we investigated the relationship between injection MA use and syringe sharing, and whether difficulty accessing sterile syringes mediated this association. Behavioral questionnaires were completed by 384 IDU in Vancouver, Canada between October 2005 and May 2008. Generalized estimating equations were used to estimate direct and indirect effects. The median age of participants was 24 (IQR: 22-27) and 214 (55.7%) were male. Injecting MA was independently associated with syringe sharing. Mediation analyses revealed that difficulty accessing sterile syringes partially mediated the association between injecting MA and syringe sharing. Interventions to reduce syringe sharing among young methamphetamine injectors must address social and structural barriers to accessing HIV prevention programs.

Original language	English
Pages (from-to)	1546-1553
Number of pages	8
Journal	AIDS and Behavior
Volume	15
Issue number	7
DOIs	https://doi.org/10.1007/s10461-010-9876-8
Publication status	Published - Oct 2011
Externally published	Yes

Bibliographical note

Funding Information:
Acknowledgments The authors thank the study participants for their contribution to the research, as well as current and past investigators and staff. We would specifically like to thank Dr. Jane Buxton, Deborah Graham, Peter Vann, Caitlin Johnston, Steve Kain, and Calvin Lai for their research and administrative assistance. The ARYS study was supported by the US National Institutes of Health (NIH) grant R01-DA028532 as well as the Canadian Institutes of Health Research (CIHR) grant MOP-102742. The VIDUS study was supported by NIH (R01-DA011591). The ACCESS study was supported by NIH (R01-DA021525) and CIHR (MOP-79297). All studies are supported by a CIHR team grant RAA-79918. Thomas Kerr is supported by the Michael Smith Foundation for Health Research (MSFHR) and the CIHR. Brandon Marshall is supported by senior graduate trainee awards from MSFHR and CIHR.

ASJC Scopus Subject Areas

Social Psychology
Public Health, Environmental and Occupational Health
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s10461-010-9876-8

Cite this

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abstract = "Injection drug users (IDU) who use methamphetamine (MA) are at an increased risk of HIV infection due to engagement in injection-related risk behavior including syringe sharing. In this cohort study of young IDU aged 18-30, we investigated the relationship between injection MA use and syringe sharing, and whether difficulty accessing sterile syringes mediated this association. Behavioral questionnaires were completed by 384 IDU in Vancouver, Canada between October 2005 and May 2008. Generalized estimating equations were used to estimate direct and indirect effects. The median age of participants was 24 (IQR: 22-27) and 214 (55.7%) were male. Injecting MA was independently associated with syringe sharing. Mediation analyses revealed that difficulty accessing sterile syringes partially mediated the association between injecting MA and syringe sharing. Interventions to reduce syringe sharing among young methamphetamine injectors must address social and structural barriers to accessing HIV prevention programs.",

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Difficulty accessing syringes mediates the relationship between methamphetamine use and syringe sharing among young injection drug users

Abstract

Bibliographical note

ASJC Scopus Subject Areas

UN SDGs

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