Dose-response association between step count and cardiovascular disease risk markers in middle-aged adults

Mark Hamer, Joanna M. Blodgett, Emmanuel Stamatakis

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

Several step-based daily targets have been widely circulated, but there is a lack of empirical population-based evidence to support such guidance. We examined dose-response associations between step count and classical CVD risk markers (glycated hemoglobin, high density lipoprotein cholesterol, triglycerides, and C-reactive protein) in 4665 adults (aged 46 years; 51.4% female) in a cross-sectional study. Step counts were measured from a thigh mounted accelerometer (activPAL) worn over 7 days. The shape of the dose-response curve for most risk markers was “L-shaped,” with linear risk reduction up to around 10 000 steps a day. Controlling for stepping intensity did not materially alter our results.

Original languageEnglish
JournalScandinavian Journal of Medicine and Science in Sports
DOIs
Publication statusAccepted/In press - 2022
Externally publishedYes

Bibliographical note

Funding Information:
British Heart Foundation grant (SP/F/20/150002)

Publisher Copyright:
© 2022 The Authors. Scandinavian Journal of Medicine & Science In Sports published by John Wiley & Sons Ltd.

ASJC Scopus Subject Areas

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

PubMed: MeSH publication types

  • Journal Article

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