Factors Associated with Willingness to Receive a COVID-19 Vaccine among 23,819 Adults Aged 50 Years or Older: An Analysis of the Canadian Longitudinal Study on Aging

Nicole E. Basta; Nazmul Sohel; Giorgia Sulis; Christina Wolfson; Geva Maimon; Lauren E. Griffith; Susan Kirkland; Jacqueline M. McMillan; Mary Thompson; Parminder Raina

doi:10.1093/aje/kwac029

Factors Associated with Willingness to Receive a COVID-19 Vaccine among 23,819 Adults Aged 50 Years or Older: An Analysis of the Canadian Longitudinal Study on Aging

Nicole E. Basta, Nazmul Sohel, Giorgia Sulis, Christina Wolfson, Geva Maimon, Lauren E. Griffith, Susan Kirkland, Jacqueline M. McMillan, Mary Thompson, Parminder Raina

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

Identifying persons who are least willing to receive a coronavirus disease 2019 (COVID-19) vaccine is critical for increasing uptake via targeted outreach. We conducted a survey of 23,819 Canadian Longitudinal Study on Aging participants from September 29 to December 29, 2020, to assess factors associated with COVID-19 vaccination willingness and reasons for willingness or lack thereof. Among adults aged 50-96 years, 84.1% (95% confidence interval (CI): 83.7, 84.6) were very or somewhat willing to receive a COVID-19 vaccine; 15.9% (95% CI: 15.4, 16.3) were uncertain or very or somewhat unwilling. Based on logistic regression, those who were younger, female, had lower education and income, were non-White, and lived in a rural area were less willing to receive a COVID-19 vaccine. After controlling for these factors, recent receipt of influenza vaccine (adjusted odds ratio = 14.3, 95% CI: 12.5, 16.2) or planning to receive influenza vaccine (adjusted odds ratio = 10.5, 95% CI: 9.5, 11.6), as compared with no receipt or planning, was most strongly associated with COVID-19 vaccination willingness. Willingness was also associated with believing one had never been infected with severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) and experiencing negative pandemic consequences. Safety concerns were most common among those unwilling. Our comprehensive assessment of COVID-19 vaccination willingness among older adults in Canada, a prioritized group for vaccination due to their risk of severe COVID-19 outcomes, provides a road map for conducting outreach to increase uptake, which is urgently needed.

Original language	English
Pages (from-to)	987-998
Number of pages	12
Journal	American Journal of Epidemiology
Volume	191
Issue number	6
DOIs	https://doi.org/10.1093/aje/kwac029
Publication status	Published - Jun 1 2022

Bibliographical note

Funding Information:
Funding for the CLSA COVID-19 Questionnaire Study was provided by the Juravinski Research Institute, the Faculty of Health Sciences of McMaster University, the Provost Fund of McMaster University, the McMaster Institute for Research on Aging, the Public Health Agency of Canada, and the Nova Scotia COVID-19 Health Research Coalition. Funding for the CLSA is provided by the government of Canada through the Canadian Institutes of Health Research (grant LSA 94473) and the Canada Foundation for Innovation. N.E.B. holds a Tier 2 Canada Research Chair in Infectious Disease Prevention. L.E.G. is supported by the McLaughlin Foundation Professorship in Population and Public Health. P.R. holds the Raymond and Margaret Labarge Chair in Optimal Aging and Knowledge Application for Optimal Aging, is the Director of the McMaster Institute for Research on Aging and the Labarge Centre for Mobility in Aging, and holds a Tier 1 Canada Research Chair in Geroscience.

Publisher Copyright:
© 2022 The Author(s) 2022.

ASJC Scopus Subject Areas

Epidemiology

PubMed: MeSH publication types

Journal Article
Research Support, Non-U.S. Gov't

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1093/aje/kwac029

Cite this

Basta, N. E., Sohel, N., Sulis, G., Wolfson, C., Maimon, G., Griffith, L. E., Kirkland, S., McMillan, J. M., Thompson, M., & Raina, P. (2022). Factors Associated with Willingness to Receive a COVID-19 Vaccine among 23,819 Adults Aged 50 Years or Older: An Analysis of the Canadian Longitudinal Study on Aging. American Journal of Epidemiology, 191(6), 987-998. https://doi.org/10.1093/aje/kwac029

Factors Associated with Willingness to Receive a COVID-19 Vaccine among 23,819 Adults Aged 50 Years or Older: An Analysis of the Canadian Longitudinal Study on Aging. / Basta, Nicole E.; Sohel, Nazmul; Sulis, Giorgia et al.
In: American Journal of Epidemiology, Vol. 191, No. 6, 01.06.2022, p. 987-998.

Research output: Contribution to journal › Article › peer-review

Basta, NE, Sohel, N, Sulis, G, Wolfson, C, Maimon, G, Griffith, LE, Kirkland, S, McMillan, JM, Thompson, M & Raina, P 2022, 'Factors Associated with Willingness to Receive a COVID-19 Vaccine among 23,819 Adults Aged 50 Years or Older: An Analysis of the Canadian Longitudinal Study on Aging', American Journal of Epidemiology, vol. 191, no. 6, pp. 987-998. https://doi.org/10.1093/aje/kwac029

@article{66a69374d12548d9b17dd7d577152b63,

title = "Factors Associated with Willingness to Receive a COVID-19 Vaccine among 23,819 Adults Aged 50 Years or Older: An Analysis of the Canadian Longitudinal Study on Aging",

abstract = "Identifying persons who are least willing to receive a coronavirus disease 2019 (COVID-19) vaccine is critical for increasing uptake via targeted outreach. We conducted a survey of 23,819 Canadian Longitudinal Study on Aging participants from September 29 to December 29, 2020, to assess factors associated with COVID-19 vaccination willingness and reasons for willingness or lack thereof. Among adults aged 50-96 years, 84.1% (95% confidence interval (CI): 83.7, 84.6) were very or somewhat willing to receive a COVID-19 vaccine; 15.9% (95% CI: 15.4, 16.3) were uncertain or very or somewhat unwilling. Based on logistic regression, those who were younger, female, had lower education and income, were non-White, and lived in a rural area were less willing to receive a COVID-19 vaccine. After controlling for these factors, recent receipt of influenza vaccine (adjusted odds ratio = 14.3, 95% CI: 12.5, 16.2) or planning to receive influenza vaccine (adjusted odds ratio = 10.5, 95% CI: 9.5, 11.6), as compared with no receipt or planning, was most strongly associated with COVID-19 vaccination willingness. Willingness was also associated with believing one had never been infected with severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) and experiencing negative pandemic consequences. Safety concerns were most common among those unwilling. Our comprehensive assessment of COVID-19 vaccination willingness among older adults in Canada, a prioritized group for vaccination due to their risk of severe COVID-19 outcomes, provides a road map for conducting outreach to increase uptake, which is urgently needed. ",

author = "Basta, {Nicole E.} and Nazmul Sohel and Giorgia Sulis and Christina Wolfson and Geva Maimon and Griffith, {Lauren E.} and Susan Kirkland and McMillan, {Jacqueline M.} and Mary Thompson and Parminder Raina",

note = "Funding Information: Funding for the CLSA COVID-19 Questionnaire Study was provided by the Juravinski Research Institute, the Faculty of Health Sciences of McMaster University, the Provost Fund of McMaster University, the McMaster Institute for Research on Aging, the Public Health Agency of Canada, and the Nova Scotia COVID-19 Health Research Coalition. Funding for the CLSA is provided by the government of Canada through the Canadian Institutes of Health Research (grant LSA 94473) and the Canada Foundation for Innovation. N.E.B. holds a Tier 2 Canada Research Chair in Infectious Disease Prevention. L.E.G. is supported by the McLaughlin Foundation Professorship in Population and Public Health. P.R. holds the Raymond and Margaret Labarge Chair in Optimal Aging and Knowledge Application for Optimal Aging, is the Director of the McMaster Institute for Research on Aging and the Labarge Centre for Mobility in Aging, and holds a Tier 1 Canada Research Chair in Geroscience. Publisher Copyright: {\textcopyright} 2022 The Author(s) 2022.",

year = "2022",

month = jun,

day = "1",

doi = "10.1093/aje/kwac029",

language = "English",

volume = "191",

pages = "987--998",

journal = "American Journal of Epidemiology",

issn = "0002-9262",

publisher = "Oxford University Press",

number = "6",

}

TY - JOUR

T1 - Factors Associated with Willingness to Receive a COVID-19 Vaccine among 23,819 Adults Aged 50 Years or Older

T2 - An Analysis of the Canadian Longitudinal Study on Aging

AU - Basta, Nicole E.

AU - Sohel, Nazmul

AU - Sulis, Giorgia

AU - Wolfson, Christina

AU - Maimon, Geva

AU - Griffith, Lauren E.

AU - Kirkland, Susan

AU - McMillan, Jacqueline M.

AU - Thompson, Mary

AU - Raina, Parminder

N1 - Funding Information: Funding for the CLSA COVID-19 Questionnaire Study was provided by the Juravinski Research Institute, the Faculty of Health Sciences of McMaster University, the Provost Fund of McMaster University, the McMaster Institute for Research on Aging, the Public Health Agency of Canada, and the Nova Scotia COVID-19 Health Research Coalition. Funding for the CLSA is provided by the government of Canada through the Canadian Institutes of Health Research (grant LSA 94473) and the Canada Foundation for Innovation. N.E.B. holds a Tier 2 Canada Research Chair in Infectious Disease Prevention. L.E.G. is supported by the McLaughlin Foundation Professorship in Population and Public Health. P.R. holds the Raymond and Margaret Labarge Chair in Optimal Aging and Knowledge Application for Optimal Aging, is the Director of the McMaster Institute for Research on Aging and the Labarge Centre for Mobility in Aging, and holds a Tier 1 Canada Research Chair in Geroscience. Publisher Copyright: © 2022 The Author(s) 2022.

PY - 2022/6/1

Y1 - 2022/6/1

N2 - Identifying persons who are least willing to receive a coronavirus disease 2019 (COVID-19) vaccine is critical for increasing uptake via targeted outreach. We conducted a survey of 23,819 Canadian Longitudinal Study on Aging participants from September 29 to December 29, 2020, to assess factors associated with COVID-19 vaccination willingness and reasons for willingness or lack thereof. Among adults aged 50-96 years, 84.1% (95% confidence interval (CI): 83.7, 84.6) were very or somewhat willing to receive a COVID-19 vaccine; 15.9% (95% CI: 15.4, 16.3) were uncertain or very or somewhat unwilling. Based on logistic regression, those who were younger, female, had lower education and income, were non-White, and lived in a rural area were less willing to receive a COVID-19 vaccine. After controlling for these factors, recent receipt of influenza vaccine (adjusted odds ratio = 14.3, 95% CI: 12.5, 16.2) or planning to receive influenza vaccine (adjusted odds ratio = 10.5, 95% CI: 9.5, 11.6), as compared with no receipt or planning, was most strongly associated with COVID-19 vaccination willingness. Willingness was also associated with believing one had never been infected with severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) and experiencing negative pandemic consequences. Safety concerns were most common among those unwilling. Our comprehensive assessment of COVID-19 vaccination willingness among older adults in Canada, a prioritized group for vaccination due to their risk of severe COVID-19 outcomes, provides a road map for conducting outreach to increase uptake, which is urgently needed.

AB - Identifying persons who are least willing to receive a coronavirus disease 2019 (COVID-19) vaccine is critical for increasing uptake via targeted outreach. We conducted a survey of 23,819 Canadian Longitudinal Study on Aging participants from September 29 to December 29, 2020, to assess factors associated with COVID-19 vaccination willingness and reasons for willingness or lack thereof. Among adults aged 50-96 years, 84.1% (95% confidence interval (CI): 83.7, 84.6) were very or somewhat willing to receive a COVID-19 vaccine; 15.9% (95% CI: 15.4, 16.3) were uncertain or very or somewhat unwilling. Based on logistic regression, those who were younger, female, had lower education and income, were non-White, and lived in a rural area were less willing to receive a COVID-19 vaccine. After controlling for these factors, recent receipt of influenza vaccine (adjusted odds ratio = 14.3, 95% CI: 12.5, 16.2) or planning to receive influenza vaccine (adjusted odds ratio = 10.5, 95% CI: 9.5, 11.6), as compared with no receipt or planning, was most strongly associated with COVID-19 vaccination willingness. Willingness was also associated with believing one had never been infected with severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) and experiencing negative pandemic consequences. Safety concerns were most common among those unwilling. Our comprehensive assessment of COVID-19 vaccination willingness among older adults in Canada, a prioritized group for vaccination due to their risk of severe COVID-19 outcomes, provides a road map for conducting outreach to increase uptake, which is urgently needed.

UR - http://www.scopus.com/inward/record.url?scp=85131701492&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85131701492&partnerID=8YFLogxK

U2 - 10.1093/aje/kwac029

DO - 10.1093/aje/kwac029

M3 - Article

C2 - 35166332

AN - SCOPUS:85131701492

SN - 0002-9262

VL - 191

SP - 987

EP - 998

JO - American Journal of Epidemiology

JF - American Journal of Epidemiology

IS - 6

ER -

Factors Associated with Willingness to Receive a COVID-19 Vaccine among 23,819 Adults Aged 50 Years or Older: An Analysis of the Canadian Longitudinal Study on Aging

Abstract

Bibliographical note

ASJC Scopus Subject Areas

PubMed: MeSH publication types

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this