Fetal kidney in organ culture: Abnormalities of development induced by decreased amounts of potassium

John F.S. Crocker, R. L. Vernier

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

Kidneys from fetal mice (10 to 18 days' gestation) were grown in organ culture. Concentrations of potassium less than 9 milliequivalents per liter (10- to 14-day kidneys), and less than 6 milliequivalents per liter (14- to 18-day kidneys), produced abnormal branching, failure of nephron induction, and occasional cystic dilatations of the ureteral bud. These studies emphasize the importance of an environment with a high concentration of potassium for development of the fetal kidney.

Original languageEnglish
Pages (from-to)485-487
Number of pages3
JournalScience
Volume169
Issue number3944
DOIs
Publication statusPublished - 1970
Externally publishedYes

ASJC Scopus Subject Areas

  • General

PubMed: MeSH publication types

  • Journal Article

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