Fish mapping and inter-Alu fingerprinting define the YAC contig map around the centromeric region of human chromosome 18

Wenda L. Greer, Melanie J. Dobson, Paul E. Neumann, Gabrielle S. Girouard, Susan M. Sparrow, D. Christie Riddell

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Previous reports concerning the location of D 18S44 with respect to the centromere have been ambiguous. Also, it has not been possible, based on formerly reported markers, to show that contigs WC 18.0 and WC 18.1 overlap. However, the data presented here definitively show, using FISH technology, that D18S44 (located on WC18.0) maps to proximal 18q. Furthermore, inter-Alu fingerprinting shows a clear overlap between WC18.0 and WC18.1, thereby establishing a complete contig between D18S44 and markers from WC18.1.

Original languageEnglish
Pages (from-to)468-470
Number of pages3
JournalGenome
Volume41
Issue number3
DOIs
Publication statusPublished - 1998

ASJC Scopus Subject Areas

  • Biotechnology
  • Molecular Biology
  • Genetics

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