Frontal Behavioral Syndromes and Functional Status in Probable Alzheimer Disease

Julie C. Stout, Mary F. Wyman, Shannon A. Johnson, Guerry M. Peavy, David P. Salmon

Research output: Contribution to journalArticlepeer-review

65 Citations (Scopus)

Abstract

Objective/Method: The authors used the Frontal Systems Behavior Scale (FrSBe) to determine the frequency of frontal behavioral syndromes in 49 subjects with mild-to-moderate dementia and 23 subjects with severe dementia of Alzheimer disease (AD) and 23 healthy control (HC) participants. Results/Conclusions: Frontal behavior syndromes occurred with higher frequency in AD. Apathy and executive dysfunction were elevated both in mild-to-moderate and severe AD. Disinhibition was elevated only in severe AD. In AD, apathy was associated with difficulty in basic activities of daily living (ADL), whereas executive dysfunction was related to impairment in instrumental ADLs.

Original languageEnglish
Pages (from-to)683-686
Number of pages4
JournalAmerican Journal of Geriatric Psychiatry
Volume11
Issue number6
DOIs
Publication statusPublished - 2003
Externally publishedYes

ASJC Scopus Subject Areas

  • Geriatrics and Gerontology
  • Psychiatry and Mental health

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