TY - GEN
T1 - High strain rate testing and structural analysis of pericardial bioprosthetic materials
AU - Lee, J. Michael
AU - Haberer, Sean A.
AU - Pereira, Christopher A.
AU - Naimark, Wendy A.
AU - Courtman, David W.
AU - Wilson, Gregory J.
PY - 1994
Y1 - 1994
N2 - Characterization of the viscoelastic behavior of pericardial biomaterials for heart valve or patching applications demands testing under loading times or frequencies typical of those that occur in physiological function or in a bioprosthetic device. We have used a servo-hydraulic testing system to evaluate the behavior of these materials under loading times as low as 0.05 s, frequencies up to 10 Hz and strain rates exceeding 24 000 %/min. Mechanical tests included large deformation cyclic loading, stress relaxation experiments, and small deformation forced vibration. This paper reviews our experience with these tests, interpreted using results from collagen denaturation temperature testing and biochemical analysis, in three distinct studies: (1) examination of the effects of glutaraldehyde, poly(glycidyl ether) (a diepoxide compound), and cyanamide on bovine pericardium, (2) comparison of bovine and porcine pericardia, and (3) evaluation of the effects of extraction of cellular components from bovine pericardium. These tools provide better means toward understanding the viscoelastic properties of these materials and the structural/functional relationships that determine those properties.
AB - Characterization of the viscoelastic behavior of pericardial biomaterials for heart valve or patching applications demands testing under loading times or frequencies typical of those that occur in physiological function or in a bioprosthetic device. We have used a servo-hydraulic testing system to evaluate the behavior of these materials under loading times as low as 0.05 s, frequencies up to 10 Hz and strain rates exceeding 24 000 %/min. Mechanical tests included large deformation cyclic loading, stress relaxation experiments, and small deformation forced vibration. This paper reviews our experience with these tests, interpreted using results from collagen denaturation temperature testing and biochemical analysis, in three distinct studies: (1) examination of the effects of glutaraldehyde, poly(glycidyl ether) (a diepoxide compound), and cyanamide on bovine pericardium, (2) comparison of bovine and porcine pericardia, and (3) evaluation of the effects of extraction of cellular components from bovine pericardium. These tools provide better means toward understanding the viscoelastic properties of these materials and the structural/functional relationships that determine those properties.
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M3 - Conference contribution
AN - SCOPUS:0028312583
SN - 0803118945
T3 - ASTM Special Technical Publication
SP - 19
EP - 42
BT - ASTM Special Technical Publication
PB - Publ by ASTM
T2 - Proceedings of the Symposium on Biomaterials' Mechanical Properties
Y2 - 14 September 1992 through 18 September 1992
ER -