Abstract
Human embryonic kidneys of 5 to 12 weeks of gestation were grown in organ culture. Potassium concentrations of 3 to 6 milliequivalents per liter produced decreased ureteral bud branching, failure of nephron induction, and occasional cystic dilatations of the ureteral bud. Normal development of the kidney occurred at potassium concentrations of 6.5 to 10 milliequivalents per liter. These studies confirm the importance of relative stability of the potassium concentration in the development of the embryonic kidney.
Original language | English |
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Pages (from-to) | 1178-1179 |
Number of pages | 2 |
Journal | Science |
Volume | 181 |
Issue number | 4105 |
DOIs | |
Publication status | Published - 1973 |
ASJC Scopus Subject Areas
- General
PubMed: MeSH publication types
- Journal Article