IgE receptors from rat intestinal mucosal and peritoneal mast cells show mast cell subtype-specific differences

M. Swieter, B. M.C. Chan, T. Lee, C. J. Rimmer, A. Froese, D. Befus

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

High- (a chain) and low-affinity IgE receptors from purified populations of rat intestinal mucosal (IMMC) and peritoneal mast cells (PMC) were characterized by SDS-PAGE. Receptor expression and molecular weight were compared. IMMC yielded 59-kilodaiton (kDa) a chains of the high-affinity receptors and two forms (58, 50 kDa) of low-affinity receptors, whereas PMC possessed only 51-kDa ra chains and 56-kDa low-affinity receptors. These differences extend the evidence for functional diversity between mast cell subtypes.

Original languageEnglish
Pages (from-to)200-202
Number of pages3
JournalInternational Archives of Allergy and Immunology
Volume88
Issue number1-2
DOIs
Publication statusPublished - 1989
Externally publishedYes

ASJC Scopus Subject Areas

  • Immunology and Allergy
  • Immunology

PubMed: MeSH publication types

  • Journal Article
  • Research Support, Non-U.S. Gov't

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