Abstract
Hypothalamic connections with the parabrachial nuclei in the cat were studied at light and electron microscopic levels following wheat germ agglutinin-horseradish peroxidase injections into the parabrachial nuclei and electrolytic lesions in the hypothalamus. The greatest concentration of retrogradely labeled neurons occurred in the paraventricular nucleus. Labeled neurons were also seen within the preoptic, anterior, lateral, dorsomedial and ventromedial hypothalamic nuclei. Hypothalamic lesions resulted in the degeneration of terminals forming axosomatic and axodendritic synapses in the parabrachial nuclei, particularly its lateral division. These findings support the idea that hypothalamic connections to specific regions of the parabrachial nuclei may underlie the topographical functional organization demonstrated for these brainstem nuclei.
| Original language | English |
|---|---|
| Pages (from-to) | 53-58 |
| Number of pages | 6 |
| Journal | Neuroscience Letters |
| Volume | 46 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Apr 20 1984 |
Bibliographical note
Funding Information:The authortsh ankD r. J.H. McLean,G .V. Allen andP . Wilkinsonf or technical assistancaen d L. Boylana nd D. Amiraultf or typingt he manuscripDtr.s . R.E. Clattenburagn dJ. McLeanp rovidedm anyh elpfulc ommentosn the manuscript. This work was supportedb y the Medical ResearchC ouncilof Canada( Grant MT7369),a ndP ostdoctoraFle llowships upportt o Y.T. from the Killam Foundation and the DalhousieM edicalR esearchF oundation.
ASJC Scopus Subject Areas
- General Neuroscience