Magnetocardiographic Functional Localization using a Current Dipole in a Realistic Torso

Jukka Nenonen, Christopher J. Purcell, B. Milan Horacek, Gerhard Stroink, Toivo Katila

Research output: Contribution to journalArticlepeer-review

75 Citations (Scopus)

Abstract

We describe a fast and numerically effective bio-magnetic inverse solution using a moving dipole in a realistic homogeneous torso. We applied the localization model and high-resolution magnetocardiographic mapping to localize noninvasively the ventricular preexcitation site in ten patients suffering from Wolff-Parkinson-White syndrome. In all cases, the computed localization results were compared to the results obtained by invasive catheter technique. Using a standard-size torso model in all cases, the average 3-D distance between the computed noninvasive locations and the invasively obtained results was 2.8 ± 1.4 cm. When the torso was rescaled to better match the true shape of the subject in five cases, the 3-D average was improved to 2.2 ± 1.0 cm. This accuracy is very satisfactory, suggesting that the method would be clinically useful.

Original languageEnglish
Pages (from-to)658-664
Number of pages7
JournalIEEE Transactions on Biomedical Engineering
Volume38
Issue number7
DOIs
Publication statusPublished - Jul 1991
Externally publishedYes

ASJC Scopus Subject Areas

  • Biomedical Engineering

PubMed: MeSH publication types

  • Journal Article

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