Mediastinal polyembryoma associated with Klinefelter syndrome

Lisa Beresford, Conrad V. Fernandez, Elizabeth Cummings, Susan Sanderson, Wei Ming-Yu, Michael Giacomantonio

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)

Abstract

A 4.5-year-old boy presented with isosexual precocious puberty and an anterior mediastinal mass. Surgical resection demonstrated a teratoma with foci of malignant mixed germ cell tumor elements of polyembryoma. On further investigation he was found to have Klinefelter syndrome. Most mediastinal germ cell tumors are treated with adjuvant therapy. He was managed with surgical excision alone and is well at 2 years follow-up. The rationale for this approach is discussed.

Original languageEnglish
Pages (from-to)321-323
Number of pages3
JournalJournal of Pediatric Hematology/Oncology
Volume25
Issue number4
DOIs
Publication statusPublished - Apr 2003

ASJC Scopus Subject Areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

PubMed: MeSH publication types

  • Case Reports
  • Journal Article
  • Review

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