Mediastinal polyembryoma associated with Klinefelter syndrome

Lisa Beresford; Conrad V. Fernandez; Elizabeth Cummings; Susan Sanderson; Wei Ming-Yu; Michael Giacomantonio

doi:10.1097/00043426-200304000-00011

Mediastinal polyembryoma associated with Klinefelter syndrome

Lisa Beresford, Conrad V. Fernandez, Elizabeth Cummings, Susan Sanderson, Wei Ming-Yu, Michael Giacomantonio

Medicine

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

Abstract

A 4.5-year-old boy presented with isosexual precocious puberty and an anterior mediastinal mass. Surgical resection demonstrated a teratoma with foci of malignant mixed germ cell tumor elements of polyembryoma. On further investigation he was found to have Klinefelter syndrome. Most mediastinal germ cell tumors are treated with adjuvant therapy. He was managed with surgical excision alone and is well at 2 years follow-up. The rationale for this approach is discussed.

Original language	English
Pages (from-to)	321-323
Number of pages	3
Journal	Journal of Pediatric Hematology/Oncology
Volume	25
Issue number	4
DOIs	https://doi.org/10.1097/00043426-200304000-00011
Publication status	Published - Apr 2003

ASJC Scopus Subject Areas

Pediatrics, Perinatology, and Child Health
Hematology
Oncology

PubMed: MeSH publication types

Case Reports
Journal Article
Review

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10.1097/00043426-200304000-00011

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abstract = "A 4.5-year-old boy presented with isosexual precocious puberty and an anterior mediastinal mass. Surgical resection demonstrated a teratoma with foci of malignant mixed germ cell tumor elements of polyembryoma. On further investigation he was found to have Klinefelter syndrome. Most mediastinal germ cell tumors are treated with adjuvant therapy. He was managed with surgical excision alone and is well at 2 years follow-up. The rationale for this approach is discussed.",

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AU - Beresford, Lisa

AU - Fernandez, Conrad V.

AU - Cummings, Elizabeth

AU - Sanderson, Susan

AU - Ming-Yu, Wei

AU - Giacomantonio, Michael

PY - 2003/4

Y1 - 2003/4

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AB - A 4.5-year-old boy presented with isosexual precocious puberty and an anterior mediastinal mass. Surgical resection demonstrated a teratoma with foci of malignant mixed germ cell tumor elements of polyembryoma. On further investigation he was found to have Klinefelter syndrome. Most mediastinal germ cell tumors are treated with adjuvant therapy. He was managed with surgical excision alone and is well at 2 years follow-up. The rationale for this approach is discussed.

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Mediastinal polyembryoma associated with Klinefelter syndrome

Abstract

ASJC Scopus Subject Areas

PubMed: MeSH publication types

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