Abstract
Sublingual nitroglycerin 0.8 mg every five minutes for a total of 4.8 mg was administered to 11 healthy volunteers. One volunteer had to withdraw due to a hypotensive bradycardic reaction after 2.4 mg. In the remaining subjects, methemoglobinemia over the next hour never significantly increased from baseline levels, reaching a peak of only 0.71%. We conclude that commonly used doses of sublingual nitroglycerin do not induce significant methemoglobinemia and that nitroglycerin would not be useful in the treatment of cyanide poisoning.
Original language | English |
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Pages (from-to) | 171-173 |
Number of pages | 3 |
Journal | Annals of Emergency Medicine |
Volume | 15 |
Issue number | 2 |
DOIs | |
Publication status | Published - Feb 1986 |
Externally published | Yes |
ASJC Scopus Subject Areas
- Emergency Medicine