Minocycline-loaded calcium polyphosphate glass microspheres as a potential drug-delivery agent for the treatment of periodontitis

Medicine & Life Sciences

• Polyphosphates 94%
• Minocycline 83%
• Periodontitis 73%
• Microspheres 68%
• Glass 64%
• Calcium 45%
• Pharmaceutical Preparations 27%
• Phosphorus 11%
• Therapeutics 11%
• Drug Liberation 10%
• Ultraviolet Spectrophotometry 9%
• Tromethamine 7%
• Calcium Chloride 7%
• In Vitro Techniques 7%
• Periodontium 7%
• Tooth Loss 7%
• Emulsions 6%
• Particle Size 5%
• Spectrum Analysis 5%
• Electron Scanning Microscopy 5%
• Magnetic Resonance Spectroscopy 4%
• Sodium 4%
• Ions 4%
• Anti-Bacterial Agents 3%
• Weights and Measures 3%

Engineering & Materials Science

• Drug delivery 90%
• Microspheres 89%
• Calcium 72%
• Glass 53%
• Phosphorus 13%
• Optical emission spectroscopy 9%
• Spectrophotometry 8%
• Nuclear magnetic resonance spectroscopy 8%
• Inductively coupled plasma 8%
• Calcium chloride 8%
• Antibiotics 7%
• Chain length 7%
• Solvent extraction 7%
• Molar ratio 6%
• Particle size analysis 6%
• Encapsulation 6%
• Emulsions 6%
• Sodium 5%
• Ions 5%
• Scanning electron microscopy 4%
• Degradation 3%

Chemical Compounds

• Glass Microsphere 100%
• Polyphosphate 77%
• Microsphere 57%
• Calcium(0) 51%
• Minocycline 35%
• Drug 14%
• Particle Size Analysis 7%
• Optical Emission Spectroscopy 7%
• Inductively Coupled Plasma 5%
• Encapsulation 4%
• Phosphorus(.) 4%
• Emulsion 4%
• Antimicrobial Agent 3%
• NMR Spectroscopy 3%
• Sodium Atom 3%
• UV/VIS Spectroscopy 3%
• Scanning Electron Microscopy 3%
• Length 3%
• Volume 3%
• Weight 2%
• Ion 2%