Modulation of cardiovascular function by Adipokines

V. DeClercq; J. E. Enns; A. Yeganeh; C. G. Taylor; P. Zahradka

doi:10.2174/1871529X11313010007

Modulation of cardiovascular function by Adipokines

V. DeClercq, J. E. Enns, A. Yeganeh, C. G. Taylor, P. Zahradka

Medicine

Research output: Contribution to journal › Review article › peer-review

20 Citations (Scopus)

Abstract

Cardiovascular disease (CVD) and associated risk factors such as obesity remain at the forefront of health concerns. Adipose tissue has been well established as an endocrine organ that becomes dysfunctional with increased adipose tissue mass. The secretion of several adipokines is altered in subjects with abdominal adiposity and these changes to the endocrine balance may contribute to increased CVD risk. The identification and characterization of disease-specific proteins within the adipose tissue offers a novel therapeutic target for prevention or treatment of cardiovascular complications. This review will discuss the latest developments on therapeutic targets within the context of adipokines, such as adiponectin, C1q/ tumor necrosis factor (TNF) related proteins (CTRPs), visfatin, vaspin, chemerin and omentin, and their involvement in obesity-related cardiovascular complications.

Original language	English
Pages (from-to)	59-72
Number of pages	14
Journal	Cardiovascular and Hematological Disorders - Drug Targets
Volume	13
Issue number	1
DOIs	https://doi.org/10.2174/1871529X11313010007
Publication status	Published - 2013

ASJC Scopus Subject Areas

Molecular Medicine
Hematology
Pharmacology
Cardiology and Cardiovascular Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.2174/1871529X11313010007

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DeClercq, V., Enns, J. E., Yeganeh, A., Taylor, C. G., & Zahradka, P. (2013). Modulation of cardiovascular function by Adipokines. Cardiovascular and Hematological Disorders - Drug Targets, 13(1), 59-72. https://doi.org/10.2174/1871529X11313010007

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AU - Yeganeh, A.

AU - Taylor, C. G.

AU - Zahradka, P.

PY - 2013

Y1 - 2013

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Modulation of cardiovascular function by Adipokines

Abstract

ASJC Scopus Subject Areas

UN SDGs

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