TY - JOUR
T1 - Molecular dimensions of gastrointestinal tumors
T2 - Some thoughts for digestion
AU - Cohen, M. Michael
PY - 2003/11/1
Y1 - 2003/11/1
N2 - Topics discussed here include PTEN mutations and colonic polyps; WNT signaling, APC, β-catenin, and gastrointestinal neoplasms; mismatch-repair genes (MLH1, MSH2, PMS1, MSH6) and hereditary nonpolyposis colorectal cancer; MYH mutations and autosomal recessive colorectal tumors; STK11 mutations and Peutz-Jeghers syndrome; TGFβ and gastrointestinal cancer; BMPR1A mutations and juvenile polyposis; FGF/FGFR alterations in gastrointestinal neoplasms; PTCH mutations and gastrointestinal neoplasms; RUNX3 expression and gastric cancer; role of mucins in gastric carcinogenesis; KIT, PDGFRα, and gastrointestinal stromal tumors; intestinal neurofibromatosis; and gastrointestinal tumors in other disorders.
AB - Topics discussed here include PTEN mutations and colonic polyps; WNT signaling, APC, β-catenin, and gastrointestinal neoplasms; mismatch-repair genes (MLH1, MSH2, PMS1, MSH6) and hereditary nonpolyposis colorectal cancer; MYH mutations and autosomal recessive colorectal tumors; STK11 mutations and Peutz-Jeghers syndrome; TGFβ and gastrointestinal cancer; BMPR1A mutations and juvenile polyposis; FGF/FGFR alterations in gastrointestinal neoplasms; PTCH mutations and gastrointestinal neoplasms; RUNX3 expression and gastric cancer; role of mucins in gastric carcinogenesis; KIT, PDGFRα, and gastrointestinal stromal tumors; intestinal neurofibromatosis; and gastrointestinal tumors in other disorders.
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U2 - 10.1002/ajmg.a.20473
DO - 10.1002/ajmg.a.20473
M3 - Article
C2 - 14518068
AN - SCOPUS:0141890121
SN - 1552-4825
VL - 122 A
SP - 303
EP - 314
JO - American Journal of Medical Genetics, Part A
JF - American Journal of Medical Genetics, Part A
IS - 4
ER -