Myomaker and Myomerger: It Takes Two to Make One

Nandini N. Margam, Roy Duncan

Research output: Contribution to journalShort surveypeer-review

5 Citations (Scopus)

Abstract

Muscle-forming myotubes are formed from the cell-cell fusion of myoblasts. In this issue of Developmental Cell, Leikina et al. (2018) provide compelling evidence that myoblast fusion is dependent on a two-component membrane fusion complex of Myomaker and Myomerger, which function in hemifusion and pore formation activity, respectively. Muscle-forming myotubes are formed from the cell-cell fusion of myoblasts. In this issue of Developmental Cell, Leikina et al. (2018) provide compelling evidence that myoblast fusion is dependent on a two-component membrane fusion complex of Myomaker and Myomerger, which function in hemifusion and pore formation activity, respectively.

Original languageEnglish
Pages (from-to)676-678
Number of pages3
JournalDevelopmental Cell
Volume46
Issue number6
DOIs
Publication statusPublished - Sept 24 2018

Bibliographical note

Publisher Copyright:
© 2018 Elsevier Inc.

ASJC Scopus Subject Areas

  • Molecular Biology
  • General Biochemistry,Genetics and Molecular Biology
  • Developmental Biology
  • Cell Biology

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