Nutritional control via Tor signaling in Saccharomyces cerevisiae

John R. Rohde; Robert Bastidas; Rekha Puria; Maria E. Cardenas

doi:10.1016/j.mib.2008.02.013

Nutritional control via Tor signaling in Saccharomyces cerevisiae

John R. Rohde, Robert Bastidas, Rekha Puria, Maria E. Cardenas

Research output: Contribution to journal › Review article › peer-review

101 Citations (Scopus)

Abstract

The yeast Saccharomyces cerevisiae senses and responds to nutrients by adapting its growth rate and undergoing morphogenic transitions to ensure survival. The Tor pathway is a major integrator of nutrient-derived signals that in coordination with other signaling pathways orchestrates cell growth. Recent advances have identified novel Tor kinase substrates and established the protein trafficking membranous network and the nucleus as platforms for Tor signaling. These and other recent findings delineate distinct signaling branches emanating from membrane-associated Tor complexes to control cell growth.

Original language	English
Pages (from-to)	153-160
Number of pages	8
Journal	Current Opinion in Microbiology
Volume	11
Issue number	2
DOIs	https://doi.org/10.1016/j.mib.2008.02.013
Publication status	Published - Apr 2008
Externally published	Yes

Bibliographical note

Funding Information:
We thank Joseph Heitman for critical reading of the manuscript and members of Mike Tyers Laboratory for discussions. This work was supported by R01 CA114107 from the National Cancer Institute (to Maria E Cardenas).

ASJC Scopus Subject Areas

Microbiology
Microbiology (medical)
Infectious Diseases

PubMed: MeSH publication types

Journal Article
Research Support, N.I.H., Extramural
Review

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.mib.2008.02.013

Cite this

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title = "Nutritional control via Tor signaling in Saccharomyces cerevisiae",

abstract = "The yeast Saccharomyces cerevisiae senses and responds to nutrients by adapting its growth rate and undergoing morphogenic transitions to ensure survival. The Tor pathway is a major integrator of nutrient-derived signals that in coordination with other signaling pathways orchestrates cell growth. Recent advances have identified novel Tor kinase substrates and established the protein trafficking membranous network and the nucleus as platforms for Tor signaling. These and other recent findings delineate distinct signaling branches emanating from membrane-associated Tor complexes to control cell growth.",

author = "Rohde, {John R.} and Robert Bastidas and Rekha Puria and Cardenas, {Maria E.}",

note = "Funding Information: We thank Joseph Heitman for critical reading of the manuscript and members of Mike Tyers Laboratory for discussions. This work was supported by R01 CA114107 from the National Cancer Institute (to Maria E Cardenas). ",

year = "2008",

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doi = "10.1016/j.mib.2008.02.013",

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AU - Rohde, John R.

AU - Bastidas, Robert

AU - Puria, Rekha

AU - Cardenas, Maria E.

N1 - Funding Information: We thank Joseph Heitman for critical reading of the manuscript and members of Mike Tyers Laboratory for discussions. This work was supported by R01 CA114107 from the National Cancer Institute (to Maria E Cardenas).

PY - 2008/4

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N2 - The yeast Saccharomyces cerevisiae senses and responds to nutrients by adapting its growth rate and undergoing morphogenic transitions to ensure survival. The Tor pathway is a major integrator of nutrient-derived signals that in coordination with other signaling pathways orchestrates cell growth. Recent advances have identified novel Tor kinase substrates and established the protein trafficking membranous network and the nucleus as platforms for Tor signaling. These and other recent findings delineate distinct signaling branches emanating from membrane-associated Tor complexes to control cell growth.

AB - The yeast Saccharomyces cerevisiae senses and responds to nutrients by adapting its growth rate and undergoing morphogenic transitions to ensure survival. The Tor pathway is a major integrator of nutrient-derived signals that in coordination with other signaling pathways orchestrates cell growth. Recent advances have identified novel Tor kinase substrates and established the protein trafficking membranous network and the nucleus as platforms for Tor signaling. These and other recent findings delineate distinct signaling branches emanating from membrane-associated Tor complexes to control cell growth.

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DO - 10.1016/j.mib.2008.02.013

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JO - Current Opinion in Microbiology

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Nutritional control via Tor signaling in Saccharomyces cerevisiae

Abstract

Bibliographical note

ASJC Scopus Subject Areas

PubMed: MeSH publication types

UN SDGs

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