TY - JOUR
T1 - Osteochondroplasty Benefits the Pragmatic Patient With Femoroacetabular Impingement
T2 - Analysis From the Embedded Prospective Cohort of the Femoroacetabular Impingement RandomiSed Controlled Trial (FIRST)
AU - FIRST Investigators
AU - Almasri, Mahmoud
AU - Simunovic, Nicole
AU - Heels-Ansdell, Diane
AU - Ayenil, Olufemi R.
AU - Ayeni, Olufemi R.
AU - Bhandari, Mohit
AU - Bedi, Asheesh
AU - Järvinen, Teppo
AU - Musahl, Volker
AU - Naudie, Douglas
AU - Seppänen, Matti
AU - Slobogean, Gerard
AU - Thabane, Lehana
AU - Duong, Andrew
AU - Skelly, Matthew
AU - Shanmugaraj, Ajay
AU - Crouch, Sarah
AU - Sprague, Sheila
AU - Buckingham, Lisa
AU - Ramsay, Tim
AU - Lee, John
AU - Kousa, Petteri
AU - Carsen, Sasha
AU - Choudur, Hema
AU - Sim, Yan
AU - Johnston, Kelly
AU - Wong, Ivan
AU - Murphy, Ryland
AU - Sparavalo, Sara
AU - Whelan, Daniel
AU - Khan, Ryan
AU - Wood, Gavin C.A.
AU - Howells, Fiona
AU - Grant, Heather
AU - Zomar, Bryn
AU - Pollock, Michael
AU - Willits, Kevin
AU - Firth, Andrew
AU - Wanlin, Stacey
AU - Remtulla, Alliya
AU - Kaniki, Nicole
AU - Belzile, Etienne L.
AU - Turmel, Sylvie
AU - Jørgensen, Uffe
AU - Gam-Pedersen, Annie
AU - Hatanpää, Tays
AU - Sihvonen, Raine
AU - Raivio, Marko
AU - Toivonen, Pirjo
AU - Routapohja, Mari Pirjetta
N1 - Funding Information:
The authors report the following potential conflicts of interest or sources of funding: O.R.A. reports grants from the Canadian Institutes of Health Research (CIHR), the American Orthopaedic Society for Sports Medicine , Canadian Orthopaedic Foundation , McMaster Surgical Associates, and Hamilton Health Sciences Department of Surgery , during the conduct of the study; and speakers bureau for CONMED. Full ICMJE author disclosure forms are available for this article online, as supplementary material .
Publisher Copyright:
© 2021 Arthroscopy Association of North America
PY - 2022/3
Y1 - 2022/3
N2 - Purpose: To determine whether arthroscopic osteochondroplasty demonstrated effectiveness in a pragmatic femoroacetabular impingement patient population embedded within FIRST (the Femoroacetabular Impingement RandomiSed controlled Trial). Methods: All cohort patients were not randomized and were followed prospectively with a follow-up assessment protocol identical to that in FIRST. The primary outcome was hip pain using a 100-point visual analog scale. Secondary outcomes included hip function (Hip Outcome Score, International Hip Outcome Tool-12), health utility (EuroQol 5 Dimensions), and health-related quality of life (Short Form-12) at 12 months, as well as operatively and nonoperatively treated hip complications at 24 months. We performed multivariable regressions to compare these outcomes between 3 groups of patients: (1) those randomized to lavage in FIRST, (2) those randomized to osteochondroplasty in FIRST, and (3) those who received osteochondroplasty as part of the cohort study. Results: All groups had improvements across all questionnaire outcomes from baseline to 12 months, with no significant differences. There were significantly more reoperations in the lavage trial group compared with those in the embedded cohort (adjusted odds ratio [aOR] 3.08; 95% confidence interval [CI] 1.23-7.73; P =.016). There were significantly more nonoperatively treated hip complications in the lavage trial group and in the osteochondroplasty trial group when compared with those in the embedded cohort (aOR 3.81; 95% CI 1.19-12.17; P =.024 and aOR 4.55; 95% CI 1.43-14.42; P =.010, respectively). Conclusions: Hip arthroscopic osteochondroplasty and lavage led to improvement in hip pain, function, and health-related quality of life at 12 months across both randomized controlled trial (RCT) and cohort patients. The pragmatic cohort receiving osteochondroplasty had (1) significantly fewer complications than RCT patients, (2) significantly less reoperations than RCT patients randomized to arthroscopic lavage, and (3) fewer, although nonsignificant, reoperations than RCT osteochondroplasty patients. Level of Evidence: II, therapeutic.
AB - Purpose: To determine whether arthroscopic osteochondroplasty demonstrated effectiveness in a pragmatic femoroacetabular impingement patient population embedded within FIRST (the Femoroacetabular Impingement RandomiSed controlled Trial). Methods: All cohort patients were not randomized and were followed prospectively with a follow-up assessment protocol identical to that in FIRST. The primary outcome was hip pain using a 100-point visual analog scale. Secondary outcomes included hip function (Hip Outcome Score, International Hip Outcome Tool-12), health utility (EuroQol 5 Dimensions), and health-related quality of life (Short Form-12) at 12 months, as well as operatively and nonoperatively treated hip complications at 24 months. We performed multivariable regressions to compare these outcomes between 3 groups of patients: (1) those randomized to lavage in FIRST, (2) those randomized to osteochondroplasty in FIRST, and (3) those who received osteochondroplasty as part of the cohort study. Results: All groups had improvements across all questionnaire outcomes from baseline to 12 months, with no significant differences. There were significantly more reoperations in the lavage trial group compared with those in the embedded cohort (adjusted odds ratio [aOR] 3.08; 95% confidence interval [CI] 1.23-7.73; P =.016). There were significantly more nonoperatively treated hip complications in the lavage trial group and in the osteochondroplasty trial group when compared with those in the embedded cohort (aOR 3.81; 95% CI 1.19-12.17; P =.024 and aOR 4.55; 95% CI 1.43-14.42; P =.010, respectively). Conclusions: Hip arthroscopic osteochondroplasty and lavage led to improvement in hip pain, function, and health-related quality of life at 12 months across both randomized controlled trial (RCT) and cohort patients. The pragmatic cohort receiving osteochondroplasty had (1) significantly fewer complications than RCT patients, (2) significantly less reoperations than RCT patients randomized to arthroscopic lavage, and (3) fewer, although nonsignificant, reoperations than RCT osteochondroplasty patients. Level of Evidence: II, therapeutic.
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U2 - 10.1016/j.arthro.2021.06.026
DO - 10.1016/j.arthro.2021.06.026
M3 - Article
C2 - 34252556
AN - SCOPUS:85111531316
SN - 0749-8063
VL - 38
SP - 818-830.e1
JO - Arthroscopy - Journal of Arthroscopic and Related Surgery
JF - Arthroscopy - Journal of Arthroscopic and Related Surgery
IS - 3
ER -