Postoperative recovery patterns following discectomy surgery in patients with lumbar radiculopathy

Shuaijin Wang; Jeffrey J. Hebert; Edward Abraham; Amanda Vandewint; Erin Bigney; Eden Richardson; Dana El-Mughayyar; Najmedden Attabib; Niels Wedderkopp; Stephen Kingwell; Alex Soroceanu; M. H. Weber; Hamilton Hall; Joel Finkelstein; Christopher S. Bailey; Kenneth Thomas; Andrew Nataraj; Jerome Paquet; Michael G. Johnson; Charles Fisher; Y. Raja Rampersaud; Nicolas Dea; Chris Small; Neil Manson

doi:10.1038/s41598-022-15169-8

Postoperative recovery patterns following discectomy surgery in patients with lumbar radiculopathy

Shuaijin Wang, Jeffrey J. Hebert, Edward Abraham, Amanda Vandewint, Erin Bigney, Eden Richardson, Dana El-Mughayyar, Najmedden Attabib, Niels Wedderkopp, Stephen Kingwell, Alex Soroceanu, M. H. Weber, Hamilton Hall, Joel Finkelstein, Christopher S. Bailey, Kenneth Thomas, Andrew Nataraj, Jerome Paquet, Michael G. Johnson, Charles FisherY. Raja Rampersaud, Nicolas Dea, Chris Small, Neil Manson

Medicine

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

This retrospective study of prospectively collected data aimed to identify unique pain and disability trajectories in patients following lumbar discectomy surgery. Patients of this study population presented chiefly with lumbar radiculopathy and underwent discectomy surgery from thirteen sites enrolled in the CSORN registry. Outcome variables of interest included numeric rating scales for leg/back pain and modified Oswestry disability index scores at baseline, 3, 12, and 24 months post-operatively. Latent class growth analysis was used to identify distinct courses in each outcome. Data from 524 patients revealed three unique trajectories for leg pain (excellent = 18.4%, good = 55.4%, poor = 26.3%), disability (excellent = 59.7%, fair = 35.6%, poor = 4.7%) and back pain (excellent = 13.0%, good = 56.4%, poor = 30.6%). Construct validity was supported by statistically significant differences in the proportions of patients attaining the criteria for minimal important change (MIC; 30%) or clinical success in disability (50% or Oswestry score ≤ 22) (p < 0.001). The variable proportions of patients belonging to poor outcome trajectories shows a disconnect between improved disability and persistence of pain. It will be beneficial to incorporate this information into the realm of patient expectation setting in concert with future findings of potential factors predictive of subgroup membership.

Original language	English
Article number	11146
Journal	Scientific Reports
Volume	12
Issue number	1
DOIs	https://doi.org/10.1038/s41598-022-15169-8
Publication status	Published - Dec 2022

Bibliographical note

Funding Information:
This study was partially supported by a CA$5,000 scholarship provided by the Dalhousie Medicine New Brunswick Research in Medicine Summer Studentship to S.W. The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Publisher Copyright:
© 2022, The Author(s).

ASJC Scopus Subject Areas

General

PubMed: MeSH publication types

Journal Article
Research Support, Non-U.S. Gov't

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10.1038/s41598-022-15169-8

Cite this

Wang, S., Hebert, J. J., Abraham, E., Vandewint, A., Bigney, E., Richardson, E., El-Mughayyar, D., Attabib, N., Wedderkopp, N., Kingwell, S., Soroceanu, A., Weber, M. H., Hall, H., Finkelstein, J., Bailey, C. S., Thomas, K., Nataraj, A., Paquet, J., Johnson, M. G., ... Manson, N. (2022). Postoperative recovery patterns following discectomy surgery in patients with lumbar radiculopathy. Scientific Reports, 12(1), Article 11146. https://doi.org/10.1038/s41598-022-15169-8

Wang, S, Hebert, JJ, Abraham, E, Vandewint, A, Bigney, E, Richardson, E, El-Mughayyar, D, Attabib, N, Wedderkopp, N, Kingwell, S, Soroceanu, A, Weber, MH, Hall, H, Finkelstein, J, Bailey, CS, Thomas, K, Nataraj, A, Paquet, J, Johnson, MG, Fisher, C, Rampersaud, YR, Dea, N, Small, C & Manson, N 2022, 'Postoperative recovery patterns following discectomy surgery in patients with lumbar radiculopathy', Scientific Reports, vol. 12, no. 1, 11146. https://doi.org/10.1038/s41598-022-15169-8

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title = "Postoperative recovery patterns following discectomy surgery in patients with lumbar radiculopathy",

abstract = "This retrospective study of prospectively collected data aimed to identify unique pain and disability trajectories in patients following lumbar discectomy surgery. Patients of this study population presented chiefly with lumbar radiculopathy and underwent discectomy surgery from thirteen sites enrolled in the CSORN registry. Outcome variables of interest included numeric rating scales for leg/back pain and modified Oswestry disability index scores at baseline, 3, 12, and 24 months post-operatively. Latent class growth analysis was used to identify distinct courses in each outcome. Data from 524 patients revealed three unique trajectories for leg pain (excellent = 18.4%, good = 55.4%, poor = 26.3%), disability (excellent = 59.7%, fair = 35.6%, poor = 4.7%) and back pain (excellent = 13.0%, good = 56.4%, poor = 30.6%). Construct validity was supported by statistically significant differences in the proportions of patients attaining the criteria for minimal important change (MIC; 30%) or clinical success in disability (50% or Oswestry score ≤ 22) (p < 0.001). The variable proportions of patients belonging to poor outcome trajectories shows a disconnect between improved disability and persistence of pain. It will be beneficial to incorporate this information into the realm of patient expectation setting in concert with future findings of potential factors predictive of subgroup membership.",

author = "Shuaijin Wang and Hebert, {Jeffrey J.} and Edward Abraham and Amanda Vandewint and Erin Bigney and Eden Richardson and Dana El-Mughayyar and Najmedden Attabib and Niels Wedderkopp and Stephen Kingwell and Alex Soroceanu and Weber, {M. H.} and Hamilton Hall and Joel Finkelstein and Bailey, {Christopher S.} and Kenneth Thomas and Andrew Nataraj and Jerome Paquet and Johnson, {Michael G.} and Charles Fisher and Rampersaud, {Y. Raja} and Nicolas Dea and Chris Small and Neil Manson",

note = "Funding Information: This study was partially supported by a CA$5,000 scholarship provided by the Dalhousie Medicine New Brunswick Research in Medicine Summer Studentship to S.W. The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Publisher Copyright: {\textcopyright} 2022, The Author(s).",

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AU - Wang, Shuaijin

AU - Hebert, Jeffrey J.

AU - Abraham, Edward

AU - Vandewint, Amanda

AU - Bigney, Erin

AU - Richardson, Eden

AU - El-Mughayyar, Dana

AU - Attabib, Najmedden

AU - Wedderkopp, Niels

AU - Kingwell, Stephen

AU - Soroceanu, Alex

AU - Weber, M. H.

AU - Hall, Hamilton

AU - Finkelstein, Joel

AU - Bailey, Christopher S.

AU - Thomas, Kenneth

AU - Nataraj, Andrew

AU - Paquet, Jerome

AU - Johnson, Michael G.

AU - Fisher, Charles

AU - Rampersaud, Y. Raja

AU - Dea, Nicolas

AU - Small, Chris

AU - Manson, Neil

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N2 - This retrospective study of prospectively collected data aimed to identify unique pain and disability trajectories in patients following lumbar discectomy surgery. Patients of this study population presented chiefly with lumbar radiculopathy and underwent discectomy surgery from thirteen sites enrolled in the CSORN registry. Outcome variables of interest included numeric rating scales for leg/back pain and modified Oswestry disability index scores at baseline, 3, 12, and 24 months post-operatively. Latent class growth analysis was used to identify distinct courses in each outcome. Data from 524 patients revealed three unique trajectories for leg pain (excellent = 18.4%, good = 55.4%, poor = 26.3%), disability (excellent = 59.7%, fair = 35.6%, poor = 4.7%) and back pain (excellent = 13.0%, good = 56.4%, poor = 30.6%). Construct validity was supported by statistically significant differences in the proportions of patients attaining the criteria for minimal important change (MIC; 30%) or clinical success in disability (50% or Oswestry score ≤ 22) (p < 0.001). The variable proportions of patients belonging to poor outcome trajectories shows a disconnect between improved disability and persistence of pain. It will be beneficial to incorporate this information into the realm of patient expectation setting in concert with future findings of potential factors predictive of subgroup membership.

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Postoperative recovery patterns following discectomy surgery in patients with lumbar radiculopathy

Abstract

Bibliographical note

ASJC Scopus Subject Areas

PubMed: MeSH publication types

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