TY - JOUR
T1 - Postoperative recovery patterns following discectomy surgery in patients with lumbar radiculopathy
AU - Wang, Shuaijin
AU - Hebert, Jeffrey J.
AU - Abraham, Edward
AU - Vandewint, Amanda
AU - Bigney, Erin
AU - Richardson, Eden
AU - El-Mughayyar, Dana
AU - Attabib, Najmedden
AU - Wedderkopp, Niels
AU - Kingwell, Stephen
AU - Soroceanu, Alex
AU - Weber, M. H.
AU - Hall, Hamilton
AU - Finkelstein, Joel
AU - Bailey, Christopher S.
AU - Thomas, Kenneth
AU - Nataraj, Andrew
AU - Paquet, Jerome
AU - Johnson, Michael G.
AU - Fisher, Charles
AU - Rampersaud, Y. Raja
AU - Dea, Nicolas
AU - Small, Chris
AU - Manson, Neil
N1 - Funding Information:
This study was partially supported by a CA$5,000 scholarship provided by the Dalhousie Medicine New Brunswick Research in Medicine Summer Studentship to S.W. The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Publisher Copyright:
© 2022, The Author(s).
PY - 2022/12
Y1 - 2022/12
N2 - This retrospective study of prospectively collected data aimed to identify unique pain and disability trajectories in patients following lumbar discectomy surgery. Patients of this study population presented chiefly with lumbar radiculopathy and underwent discectomy surgery from thirteen sites enrolled in the CSORN registry. Outcome variables of interest included numeric rating scales for leg/back pain and modified Oswestry disability index scores at baseline, 3, 12, and 24 months post-operatively. Latent class growth analysis was used to identify distinct courses in each outcome. Data from 524 patients revealed three unique trajectories for leg pain (excellent = 18.4%, good = 55.4%, poor = 26.3%), disability (excellent = 59.7%, fair = 35.6%, poor = 4.7%) and back pain (excellent = 13.0%, good = 56.4%, poor = 30.6%). Construct validity was supported by statistically significant differences in the proportions of patients attaining the criteria for minimal important change (MIC; 30%) or clinical success in disability (50% or Oswestry score ≤ 22) (p < 0.001). The variable proportions of patients belonging to poor outcome trajectories shows a disconnect between improved disability and persistence of pain. It will be beneficial to incorporate this information into the realm of patient expectation setting in concert with future findings of potential factors predictive of subgroup membership.
AB - This retrospective study of prospectively collected data aimed to identify unique pain and disability trajectories in patients following lumbar discectomy surgery. Patients of this study population presented chiefly with lumbar radiculopathy and underwent discectomy surgery from thirteen sites enrolled in the CSORN registry. Outcome variables of interest included numeric rating scales for leg/back pain and modified Oswestry disability index scores at baseline, 3, 12, and 24 months post-operatively. Latent class growth analysis was used to identify distinct courses in each outcome. Data from 524 patients revealed three unique trajectories for leg pain (excellent = 18.4%, good = 55.4%, poor = 26.3%), disability (excellent = 59.7%, fair = 35.6%, poor = 4.7%) and back pain (excellent = 13.0%, good = 56.4%, poor = 30.6%). Construct validity was supported by statistically significant differences in the proportions of patients attaining the criteria for minimal important change (MIC; 30%) or clinical success in disability (50% or Oswestry score ≤ 22) (p < 0.001). The variable proportions of patients belonging to poor outcome trajectories shows a disconnect between improved disability and persistence of pain. It will be beneficial to incorporate this information into the realm of patient expectation setting in concert with future findings of potential factors predictive of subgroup membership.
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U2 - 10.1038/s41598-022-15169-8
DO - 10.1038/s41598-022-15169-8
M3 - Article
C2 - 35778472
AN - SCOPUS:85133257811
SN - 2045-2322
VL - 12
JO - Scientific Reports
JF - Scientific Reports
IS - 1
M1 - 11146
ER -