Recommendations for the use of rotavirus vaccines in infants

Robert Bortolussi, Jane Finlay, Jane C. McDonald, Heather Onyett, Joan L. Robinson, Élisabeth Rousseau-Harsany, Upton D. Allen, Charles P.S. Hui, Larry Pickering, James Kellner, Noni E. MacDonald, Dorothy L. Moore, Marina I. Salvadori, Nicole Le Saux

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

Rotavirus infection occurs in the majority of healthy children before five years of age, and is the most common diarrheal illness associated with hospitalization. The majority of children present with symptoms of vomiting, diarrhea and fever. As a result, rotavirus gastroenteritis is responsible for greater morbidity than other common childhood diarrheal illnesses. The highest risk of severe disease is in children younger than two years of age. It is estimated that one in 20 children will require an emergency department visit. In addition to community-acquired infections, hospital-acquired infections are also significant. There are currently two licensed rotavirus vaccines in Canada. Both vaccines are administered orally and are highly effective against severe disease and hospitalization. Large pre- and postmarketing studies have shown no increased risk of intussusception with the current rotavirus vaccines. The present statement provides information concerning the clinical disease and rotavirus vaccines in Canada.

Original languageEnglish
Pages (from-to)519-523
Number of pages5
JournalPaediatrics and Child Health
Volume15
Issue number8
DOIs
Publication statusPublished - Oct 2010
Externally publishedYes

ASJC Scopus Subject Areas

  • Pediatrics, Perinatology, and Child Health

PubMed: MeSH publication types

  • Journal Article

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