Regionální metabolizmus mozku a příznaky schizofrenie studie pozitronové emisní tomografie (PET)

J. Horáček; M. Kopeček; L. Linhartová; O. Bělohlávek; D. Janeba; F. Španiel; T. Hájek

Regionální metabolizmus mozku a příznaky schizofrenie studie pozitronové emisní tomografie (PET)

Translated title of the contribution: Regional brain metabolism and symptoms of schizophrenia pozitron emission tomography (PET) study

J. Horáček, M. Kopeček, L. Linhartová, O. Bělohlávek, D. Janeba, F. Španiel, T. Hájek

Research output: Contribution to journal › Article › peer-review

Abstract

By the use of ¹⁸FDG we investigated the group of 18 schizophrenic subjects (11 females and 7 males). Regional brain metabolism has been measured in resting state in selected regions of interest (ROI) of two horizontal sections. Total PANSS score negatively correlates with decrease of metabolism in insular regions bilaterally, with left nucleus caudatus and left dorsal temporal region. Positive symptoms are associated with decrease of metabolism in globus pallidus, nucleus putamen and temporo-parietal kortex. Negative symptoms are associated with decrease of prefrontal, insular, temporal and caudate metabolism on the both sides. On the upper slide negative symptoms have been also correlated with low left fronto-temporo-parietal metabolism. Anxiety during the PET investigation has increased metabolism in some regions. Our study demonstrates dysfunction in brain parts involved in schizophrenia disorder.

Translated title of the contribution	Regional brain metabolism and symptoms of schizophrenia pozitron emission tomography (PET) study
Original language	Czech
Pages (from-to)	32-36
Number of pages	5
Journal	Psychiatrie
Volume	5
Issue number	SUPPL. 3
Publication status	Published - 2001
Externally published	Yes

ASJC Scopus Subject Areas

Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

@article{41bacdb43ccb466d84968527e5f2e556,

title = "Region{\'a}ln{\'i} metabolizmus mozku a p{\v r}{\'i}znaky schizofrenie studie pozitronov{\'e} emisn{\'i} tomografie (PET)",

abstract = "By the use of 18FDG we investigated the group of 18 schizophrenic subjects (11 females and 7 males). Regional brain metabolism has been measured in resting state in selected regions of interest (ROI) of two horizontal sections. Total PANSS score negatively correlates with decrease of metabolism in insular regions bilaterally, with left nucleus caudatus and left dorsal temporal region. Positive symptoms are associated with decrease of metabolism in globus pallidus, nucleus putamen and temporo-parietal kortex. Negative symptoms are associated with decrease of prefrontal, insular, temporal and caudate metabolism on the both sides. On the upper slide negative symptoms have been also correlated with low left fronto-temporo-parietal metabolism. Anxiety during the PET investigation has increased metabolism in some regions. Our study demonstrates dysfunction in brain parts involved in schizophrenia disorder.",

author = "J. Hor{\'a}{\v c}ek and M. Kope{\v c}ek and L. Linhartov{\'a} and O. B{\v e}lohl{\'a}vek and D. Janeba and F. {\v S}paniel and T. H{\'a}jek",

year = "2001",

language = "Tch{\`e}que",

volume = "5",

pages = "32--36",

journal = "Psychiatrie",

issn = "1211-7579",

publisher = "TIGIS Spol. s.r.o.",

number = "SUPPL. 3",

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TY - JOUR

T1 - Regionální metabolizmus mozku a příznaky schizofrenie studie pozitronové emisní tomografie (PET)

AU - Horáček, J.

AU - Kopeček, M.

AU - Linhartová, L.

AU - Bělohlávek, O.

AU - Janeba, D.

AU - Španiel, F.

AU - Hájek, T.

PY - 2001

Y1 - 2001

N2 - By the use of 18FDG we investigated the group of 18 schizophrenic subjects (11 females and 7 males). Regional brain metabolism has been measured in resting state in selected regions of interest (ROI) of two horizontal sections. Total PANSS score negatively correlates with decrease of metabolism in insular regions bilaterally, with left nucleus caudatus and left dorsal temporal region. Positive symptoms are associated with decrease of metabolism in globus pallidus, nucleus putamen and temporo-parietal kortex. Negative symptoms are associated with decrease of prefrontal, insular, temporal and caudate metabolism on the both sides. On the upper slide negative symptoms have been also correlated with low left fronto-temporo-parietal metabolism. Anxiety during the PET investigation has increased metabolism in some regions. Our study demonstrates dysfunction in brain parts involved in schizophrenia disorder.

AB - By the use of 18FDG we investigated the group of 18 schizophrenic subjects (11 females and 7 males). Regional brain metabolism has been measured in resting state in selected regions of interest (ROI) of two horizontal sections. Total PANSS score negatively correlates with decrease of metabolism in insular regions bilaterally, with left nucleus caudatus and left dorsal temporal region. Positive symptoms are associated with decrease of metabolism in globus pallidus, nucleus putamen and temporo-parietal kortex. Negative symptoms are associated with decrease of prefrontal, insular, temporal and caudate metabolism on the both sides. On the upper slide negative symptoms have been also correlated with low left fronto-temporo-parietal metabolism. Anxiety during the PET investigation has increased metabolism in some regions. Our study demonstrates dysfunction in brain parts involved in schizophrenia disorder.

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UR - http://www.scopus.com/inward/citedby.url?scp=0034820276&partnerID=8YFLogxK

M3 - Artículo

AN - SCOPUS:0034820276

SN - 1211-7579

VL - 5

SP - 32

EP - 36

JO - Psychiatrie

JF - Psychiatrie

IS - SUPPL. 3

ER -

Regionální metabolizmus mozku a příznaky schizofrenie studie pozitronové emisní tomografie (PET)

Abstract

ASJC Scopus Subject Areas

UN SDGs

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