Resolving sex and gender bias in COVID-19 vaccines R&D and beyond

Lavanya Vijayasingham; Shirin Heidari; Jean Munro; Saad Omer; Noni MacDonald

doi:10.1080/21645515.2022.2035142

Resolving sex and gender bias in COVID-19 vaccines R&D and beyond

Lavanya Vijayasingham, Shirin Heidari, Jean Munro, Saad Omer, Noni MacDonald

Medicine

Research output: Contribution to journal › Comment/debate › peer-review

5 Citations (Scopus)

Abstract

The influence of sex and gender in immune response and vaccine outcomes is established in many disease areas, including in COVID-19. Yet, there are notable gaps in the consideration of sex and gender in the analysis and reporting of COVID-19 vaccines clinical trial data. The push for stronger sex and gender integration in vaccines science should be championed by all researchers and stakeholders across the R&D and access ecosystem–not just gender experts. This requires joint action on the tactical framing of customized value propositions (based on stakeholder motivations), the stronger enforcement of existing regulation, tools, and commitments, and aligning the overall agenda to parallel calls on intersectionality, equity diversity and inclusion.

Original language	English
Article number	2035142
Journal	Human Vaccines and Immunotherapeutics
Volume	18
Issue number	1
DOIs	https://doi.org/10.1080/21645515.2022.2035142
Publication status	Published - 2022

Bibliographical note

Funding Information:
This work is led by The Gender and Health Hub at UNU-IIGH, which receives grant funding from the Bill and Melinda Gates Foundation.

Publisher Copyright:
© 2022 The Author(s). Published with license by Taylor & Francis Group, LLC.

ASJC Scopus Subject Areas

Immunology and Allergy
Immunology
Pharmacology

PubMed: MeSH publication types

Journal Article
Research Support, Non-U.S. Gov't

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1080/21645515.2022.2035142

Cite this

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abstract = "The influence of sex and gender in immune response and vaccine outcomes is established in many disease areas, including in COVID-19. Yet, there are notable gaps in the consideration of sex and gender in the analysis and reporting of COVID-19 vaccines clinical trial data. The push for stronger sex and gender integration in vaccines science should be championed by all researchers and stakeholders across the R&D and access ecosystem–not just gender experts. This requires joint action on the tactical framing of customized value propositions (based on stakeholder motivations), the stronger enforcement of existing regulation, tools, and commitments, and aligning the overall agenda to parallel calls on intersectionality, equity diversity and inclusion.",

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Resolving sex and gender bias in COVID-19 vaccines R&D and beyond

Abstract

Bibliographical note

ASJC Scopus Subject Areas

PubMed: MeSH publication types

UN SDGs

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