Risk factors for cytomegalovirus seropositivity in a population of day care educators in Montréal, Canada

Serene A. Joseph; Claire Beliveau; Cristin J. Muecke; Elham Rahme; Julio C. Soto; Gordon Flowerdew; Lynn Johnston; Donald Langille; Theresa W. Gyorkos

doi:10.1093/occmed/kqi121

Risk factors for cytomegalovirus seropositivity in a population of day care educators in Montréal, Canada

Serene A. Joseph, Claire Beliveau, Cristin J. Muecke, Elham Rahme, Julio C. Soto, Gordon Flowerdew, Lynn Johnston, Donald Langille, Theresa W. Gyorkos

Medicine

Medicine

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

Background: Horizontal transmission of cytomegalovirus (CMV) is common in the day care setting. Day care educators appear to be at a high risk of infection; however, studies are limited. Aims: To determine the proportion of CMV-seropositive female educators in the day care setting and to identify associated risk factors. Methods: Educator- and day care-level risk factors for CMV seropositivity were obtained by questionnaires from day care educators and directors, respectively. Sera were collected from educators and analyzed by enzyme-linked immunosorbent assay. Significant independent risk factors for CMV seropositivity were determined using a multivariable logistic regression model which was fitted using the generalized estimating equation method. Results: CMV seroprevalence in 473 female educators from 81 day care centers in Montréal, Canada, was 57%. Significant risk factors for CMV seropositivity were (i) increasing age (OR_5-yr = 1.19; 95% CI = 1.05-1.35), (ii) low-income country of birth (OR = 10.23; 95% CI = 2.64-39.50) or middle-income country of birth (OR = 4.99; 95% CI = 2.39-10.40), (iii) having ≥2 children of their own (OR = 1.98; 95% CI = 1.19-3.31) and (iv) child-to-educator ratio >6 (18-35 months old) in a day care center (OR = 1.87; 95% CI = 1.25-2.81). Conclusions: Day care educators have risks for CMV infection related to their work in the day care setting, as well as personal risk factors. A review of current guidelines for the prevention of CMV infection in day care is needed to ensure that recommendations are evidence based.

Original language	English
Pages (from-to)	564-567
Number of pages	4
Journal	Occupational Medicine
Volume	55
Issue number	7
DOIs	https://doi.org/10.1093/occmed/kqi121
Publication status	Published - Oct 2005

Bibliographical note

Funding Information:
We thank Youssef Toubouti for his assistance with the data analysis. This study was financially supported by GlaxoSmithKline Inc. for serologic analyses.

ASJC Scopus Subject Areas

Public Health, Environmental and Occupational Health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1093/occmed/kqi121

Cite this

@article{918b31c87f69491aa79d65d4fdc5bf57,

title = "Risk factors for cytomegalovirus seropositivity in a population of day care educators in Montr{\'e}al, Canada",

abstract = "Background: Horizontal transmission of cytomegalovirus (CMV) is common in the day care setting. Day care educators appear to be at a high risk of infection; however, studies are limited. Aims: To determine the proportion of CMV-seropositive female educators in the day care setting and to identify associated risk factors. Methods: Educator- and day care-level risk factors for CMV seropositivity were obtained by questionnaires from day care educators and directors, respectively. Sera were collected from educators and analyzed by enzyme-linked immunosorbent assay. Significant independent risk factors for CMV seropositivity were determined using a multivariable logistic regression model which was fitted using the generalized estimating equation method. Results: CMV seroprevalence in 473 female educators from 81 day care centers in Montr{\'e}al, Canada, was 57%. Significant risk factors for CMV seropositivity were (i) increasing age (OR5-yr = 1.19; 95% CI = 1.05-1.35), (ii) low-income country of birth (OR = 10.23; 95% CI = 2.64-39.50) or middle-income country of birth (OR = 4.99; 95% CI = 2.39-10.40), (iii) having ≥2 children of their own (OR = 1.98; 95% CI = 1.19-3.31) and (iv) child-to-educator ratio >6 (18-35 months old) in a day care center (OR = 1.87; 95% CI = 1.25-2.81). Conclusions: Day care educators have risks for CMV infection related to their work in the day care setting, as well as personal risk factors. A review of current guidelines for the prevention of CMV infection in day care is needed to ensure that recommendations are evidence based.",

author = "Joseph, {Serene A.} and Claire Beliveau and Muecke, {Cristin J.} and Elham Rahme and Soto, {Julio C.} and Gordon Flowerdew and Lynn Johnston and Donald Langille and Gyorkos, {Theresa W.}",

note = "Funding Information: We thank Youssef Toubouti for his assistance with the data analysis. This study was financially supported by GlaxoSmithKline Inc. for serologic analyses.",

year = "2005",

month = oct,

doi = "10.1093/occmed/kqi121",

language = "English",

volume = "55",

pages = "564--567",

journal = "Occupational Medicine",

issn = "0962-7480",

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T1 - Risk factors for cytomegalovirus seropositivity in a population of day care educators in Montréal, Canada

AU - Joseph, Serene A.

AU - Beliveau, Claire

AU - Muecke, Cristin J.

AU - Rahme, Elham

AU - Soto, Julio C.

AU - Flowerdew, Gordon

AU - Johnston, Lynn

AU - Langille, Donald

AU - Gyorkos, Theresa W.

N1 - Funding Information: We thank Youssef Toubouti for his assistance with the data analysis. This study was financially supported by GlaxoSmithKline Inc. for serologic analyses.

PY - 2005/10

Y1 - 2005/10

N2 - Background: Horizontal transmission of cytomegalovirus (CMV) is common in the day care setting. Day care educators appear to be at a high risk of infection; however, studies are limited. Aims: To determine the proportion of CMV-seropositive female educators in the day care setting and to identify associated risk factors. Methods: Educator- and day care-level risk factors for CMV seropositivity were obtained by questionnaires from day care educators and directors, respectively. Sera were collected from educators and analyzed by enzyme-linked immunosorbent assay. Significant independent risk factors for CMV seropositivity were determined using a multivariable logistic regression model which was fitted using the generalized estimating equation method. Results: CMV seroprevalence in 473 female educators from 81 day care centers in Montréal, Canada, was 57%. Significant risk factors for CMV seropositivity were (i) increasing age (OR5-yr = 1.19; 95% CI = 1.05-1.35), (ii) low-income country of birth (OR = 10.23; 95% CI = 2.64-39.50) or middle-income country of birth (OR = 4.99; 95% CI = 2.39-10.40), (iii) having ≥2 children of their own (OR = 1.98; 95% CI = 1.19-3.31) and (iv) child-to-educator ratio >6 (18-35 months old) in a day care center (OR = 1.87; 95% CI = 1.25-2.81). Conclusions: Day care educators have risks for CMV infection related to their work in the day care setting, as well as personal risk factors. A review of current guidelines for the prevention of CMV infection in day care is needed to ensure that recommendations are evidence based.

AB - Background: Horizontal transmission of cytomegalovirus (CMV) is common in the day care setting. Day care educators appear to be at a high risk of infection; however, studies are limited. Aims: To determine the proportion of CMV-seropositive female educators in the day care setting and to identify associated risk factors. Methods: Educator- and day care-level risk factors for CMV seropositivity were obtained by questionnaires from day care educators and directors, respectively. Sera were collected from educators and analyzed by enzyme-linked immunosorbent assay. Significant independent risk factors for CMV seropositivity were determined using a multivariable logistic regression model which was fitted using the generalized estimating equation method. Results: CMV seroprevalence in 473 female educators from 81 day care centers in Montréal, Canada, was 57%. Significant risk factors for CMV seropositivity were (i) increasing age (OR5-yr = 1.19; 95% CI = 1.05-1.35), (ii) low-income country of birth (OR = 10.23; 95% CI = 2.64-39.50) or middle-income country of birth (OR = 4.99; 95% CI = 2.39-10.40), (iii) having ≥2 children of their own (OR = 1.98; 95% CI = 1.19-3.31) and (iv) child-to-educator ratio >6 (18-35 months old) in a day care center (OR = 1.87; 95% CI = 1.25-2.81). Conclusions: Day care educators have risks for CMV infection related to their work in the day care setting, as well as personal risk factors. A review of current guidelines for the prevention of CMV infection in day care is needed to ensure that recommendations are evidence based.

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DO - 10.1093/occmed/kqi121

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Risk factors for cytomegalovirus seropositivity in a population of day care educators in Montréal, Canada

Abstract

Bibliographical note

ASJC Scopus Subject Areas

UN SDGs

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