Scaling the microrheology of living cells

Ben Fabry; Geoffrey N. Maksym; James P. Butler; Michael Glogauer; Daniel Navajas; Jeffrey J. Fredberg

doi:10.1103/PhysRevLett.87.148102

Scaling the microrheology of living cells

Ben Fabry, Geoffrey N. Maksym, James P. Butler, Michael Glogauer, Daniel Navajas, Jeffrey J. Fredberg

Medicine

Research output: Contribution to journal › Article › peer-review

720 Citations (Scopus)

Abstract

A rheological behavior is introduced that stands in contrast with prevailing theories of cell mechanics. This behavior holds that cell rheology arises from an interaction of distinct elastic and viscous components expressing a limited range of characteristic relaxation times. The data given support the hypothesis that the locus of both the frictional and the elastic stresses is within formed structures of the cytoskeleton and that the dominant frictional stress does not correspond to a viscous stress.

Original language	English
Article number	148102
Pages (from-to)	148102/1-148102/4
Journal	Physical Review Letters
Volume	87
Issue number	14
DOIs	https://doi.org/10.1103/PhysRevLett.87.148102
Publication status	Published - Oct 1 2001

ASJC Scopus Subject Areas

General Physics and Astronomy

Access to Document

10.1103/PhysRevLett.87.148102

Cite this

@article{7573139b01f546e084838b7475685eb7,

title = "Scaling the microrheology of living cells",

abstract = "A rheological behavior is introduced that stands in contrast with prevailing theories of cell mechanics. This behavior holds that cell rheology arises from an interaction of distinct elastic and viscous components expressing a limited range of characteristic relaxation times. The data given support the hypothesis that the locus of both the frictional and the elastic stresses is within formed structures of the cytoskeleton and that the dominant frictional stress does not correspond to a viscous stress.",

author = "Ben Fabry and Maksym, {Geoffrey N.} and Butler, {James P.} and Michael Glogauer and Daniel Navajas and Fredberg, {Jeffrey J.}",

year = "2001",

month = oct,

day = "1",

doi = "10.1103/PhysRevLett.87.148102",

language = "English",

volume = "87",

pages = "148102/1--148102/4",

journal = "Physical Review Letters",

issn = "0031-9007",

publisher = "American Physical Society",

number = "14",

}

TY - JOUR

T1 - Scaling the microrheology of living cells

AU - Fabry, Ben

AU - Maksym, Geoffrey N.

AU - Butler, James P.

AU - Glogauer, Michael

AU - Navajas, Daniel

AU - Fredberg, Jeffrey J.

PY - 2001/10/1

Y1 - 2001/10/1

N2 - A rheological behavior is introduced that stands in contrast with prevailing theories of cell mechanics. This behavior holds that cell rheology arises from an interaction of distinct elastic and viscous components expressing a limited range of characteristic relaxation times. The data given support the hypothesis that the locus of both the frictional and the elastic stresses is within formed structures of the cytoskeleton and that the dominant frictional stress does not correspond to a viscous stress.

AB - A rheological behavior is introduced that stands in contrast with prevailing theories of cell mechanics. This behavior holds that cell rheology arises from an interaction of distinct elastic and viscous components expressing a limited range of characteristic relaxation times. The data given support the hypothesis that the locus of both the frictional and the elastic stresses is within formed structures of the cytoskeleton and that the dominant frictional stress does not correspond to a viscous stress.

UR - http://www.scopus.com/inward/record.url?scp=42749104581&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=42749104581&partnerID=8YFLogxK

U2 - 10.1103/PhysRevLett.87.148102

DO - 10.1103/PhysRevLett.87.148102

M3 - Article

AN - SCOPUS:42749104581

SN - 0031-9007

VL - 87

SP - 148102/1-148102/4

JO - Physical Review Letters

JF - Physical Review Letters

IS - 14

M1 - 148102

ER -

Scaling the microrheology of living cells

Abstract

ASJC Scopus Subject Areas

Access to Document

Other files and links

Fingerprint

Cite this