TY - JOUR
T1 - Semantic monitoring of words with emotional connotation during fMRI
T2 - Contribution of anterior left frontal cortex
AU - Crosson, Bruce
AU - Cato, M. Allison
AU - Sadek, Joseph R.
AU - Gökçay, Didem
AU - Bauer, Russell M.
AU - Fischler, Ira S.
AU - Maron, Leeza
AU - Gopinath, Kaundinya
AU - Auerbach, Edward J.
AU - Browd, Samuel R.
AU - Briggs, Richard W.
PY - 2002
Y1 - 2002
N2 - Previous studies showed that cortex in the anterior portions of the left frontal and temporal lobes participates in generating words with emotional connotations and processing pictures with emotional content. If these cortices process the semantic attribute of emotional connotation, they should be active whenever processing emotional connotation, without respect to modality of input or mode of output. Thus, we hypothesized that they would activate during monitoring of words with emotional connotations. Sixteen normal subjects performed semantic monitoring of words with emotional connotations, animal names, and implement names during fMRI. Cortex in the anterior left frontal lobe demonstrated significant activity for monitoring words with emotional connotations compared to monitoring tone sequences, animal names, or implement names. Together, the current and previous results implicate cortex in the anterior left frontal lobe in semantic processing of emotional connotation, consistent with connections of this cortex to paralimbic association areas. Current findings also indicate that neural substrates for processing emotional connotation are independent of substrates for processing the categories of living and nonliving things.
AB - Previous studies showed that cortex in the anterior portions of the left frontal and temporal lobes participates in generating words with emotional connotations and processing pictures with emotional content. If these cortices process the semantic attribute of emotional connotation, they should be active whenever processing emotional connotation, without respect to modality of input or mode of output. Thus, we hypothesized that they would activate during monitoring of words with emotional connotations. Sixteen normal subjects performed semantic monitoring of words with emotional connotations, animal names, and implement names during fMRI. Cortex in the anterior left frontal lobe demonstrated significant activity for monitoring words with emotional connotations compared to monitoring tone sequences, animal names, or implement names. Together, the current and previous results implicate cortex in the anterior left frontal lobe in semantic processing of emotional connotation, consistent with connections of this cortex to paralimbic association areas. Current findings also indicate that neural substrates for processing emotional connotation are independent of substrates for processing the categories of living and nonliving things.
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U2 - 10.1017/S1355617702801394
DO - 10.1017/S1355617702801394
M3 - Article
C2 - 12164671
AN - SCOPUS:0036637846
SN - 1355-6177
VL - 8
SP - 607
EP - 622
JO - Journal of the International Neuropsychological Society
JF - Journal of the International Neuropsychological Society
IS - 5
ER -