Stem cells and regenerative medicine - future perspectives

Keith R. Brunt, Richard D. Weisel, Ren Ke Li

Research output: Contribution to journalArticlepeer-review

57 Citations (Scopus)

Abstract

Stem cell research has expanded at an exponential rate, but its therapeutic applications have progressed much more slowly. Currently, the research focuses on understanding embryonic, adult, and inducible pluripotent stem cells. Translation of adult stem cell research has established a definitive benefit that is greater than that of the current standard of care in the field of cardiovascular medicine. The future of stem cell research and therapy will continue to provide novel avenues of diagnostics, therapeutics, and tissue regeneration. Here we discuss a brief history of stem cell research as it transitioned from the 20th to the 21st century. We address lessons learned in the first decade of the new millennium that could help guide others to translate research into therapy across disciplines. Finally, we highlight future goals and challenges that must be overcome and offer some perspective on the bright future of stem cell research and therapy.

Original languageEnglish
Pages (from-to)327-335
Number of pages9
JournalCanadian Journal of Physiology and Pharmacology
Volume90
Issue number3
DOIs
Publication statusPublished - Mar 2012
Externally publishedYes

ASJC Scopus Subject Areas

  • Physiology
  • Pharmacology
  • Physiology (medical)

PubMed: MeSH publication types

  • Journal Article
  • Research Support, Non-U.S. Gov't
  • Review

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