Abstract
Mass spectrometric studies are now playing a leading role in the elucidation of lipopolysaccharide (LPS) structures through the characterization of antigenic polysaccharides, core oligosaccharides and lipid A components including LPS genetic modifications. The conventional MS and MS/MS analyses together with CID fragmentation provide additional structural information complementary to the previous analytical experiments, and thus contribute to an integrated strategy for the simultaneous characterization and correct sequencing of the carbohydrate moiety.
Original language | English |
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Pages (from-to) | 606-650 |
Number of pages | 45 |
Journal | Mass Spectrometry Reviews |
Volume | 29 |
Issue number | 4 |
DOIs | |
Publication status | Published - 2010 |
Externally published | Yes |
ASJC Scopus Subject Areas
- Analytical Chemistry
- Condensed Matter Physics
- General Biochemistry,Genetics and Molecular Biology
- Spectroscopy