Substantia nigra projections to the reticular formation, superior colliculus and central gray in the rat, cat and monkey

David A. Hopkins; Louis W. Niessen

doi:10.1016/0304-3940(76)90156-7

Substantia nigra projections to the reticular formation, superior colliculus and central gray in the rat, cat and monkey

David A. Hopkins, Louis W. Niessen

Research output: Contribution to journal › Article › peer-review

250 Citations (Scopus)

Abstract

After horseradish peroxidase injections in different parts of the lower brain stem retrogradely labeled neurons were observed in the substantia nigra, mainly ipsilateral pars reticulata. These findings demonstrate that the substantia nigra projects not only to the striatum and thalamus but also to brain stem areas which give rise to descending spinal projections. These nigral projections to brain stem structures may play an important role in a variety of behaviors and may be involved in clinical syndromes associated with nigral lesions.

Original language	English
Pages (from-to)	253-259
Number of pages	7
Journal	Neuroscience Letters
Volume	2
Issue number	5
DOIs	https://doi.org/10.1016/0304-3940(76)90156-7
Publication status	Published - Jul 1976
Externally published	Yes

Bibliographical note

Funding Information:
This investigation was supported in part by Grant 13-46-15 of the Dutch Organization for Fundamental Research in Medicine (FUNGO). We thank Drs. H.G.J.M. Kuypers and L. Moll for many helpful suggestions and Mr. E. Dalm, Miss P.C. Delfos, Mrs. E. Jongbloed-Klink, Miss F. Kwee and Mr. W. v.d. Oudenalder for technical assistance.

ASJC Scopus Subject Areas

General Neuroscience

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10.1016/0304-3940(76)90156-7

Cite this

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title = "Substantia nigra projections to the reticular formation, superior colliculus and central gray in the rat, cat and monkey",

abstract = "After horseradish peroxidase injections in different parts of the lower brain stem retrogradely labeled neurons were observed in the substantia nigra, mainly ipsilateral pars reticulata. These findings demonstrate that the substantia nigra projects not only to the striatum and thalamus but also to brain stem areas which give rise to descending spinal projections. These nigral projections to brain stem structures may play an important role in a variety of behaviors and may be involved in clinical syndromes associated with nigral lesions.",

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doi = "10.1016/0304-3940(76)90156-7",

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AU - Hopkins, David A.

AU - Niessen, Louis W.

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AB - After horseradish peroxidase injections in different parts of the lower brain stem retrogradely labeled neurons were observed in the substantia nigra, mainly ipsilateral pars reticulata. These findings demonstrate that the substantia nigra projects not only to the striatum and thalamus but also to brain stem areas which give rise to descending spinal projections. These nigral projections to brain stem structures may play an important role in a variety of behaviors and may be involved in clinical syndromes associated with nigral lesions.

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Substantia nigra projections to the reticular formation, superior colliculus and central gray in the rat, cat and monkey

Abstract

Bibliographical note

ASJC Scopus Subject Areas

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